Evidence map›Paper›PMID 30429251›Full record

ArticleJournal of clinical microbiology2019

Clinical Performance of the BioPlex 2200 Syphilis Total & RPR Assay at a Tertiary Medical Center with a High Rate of Syphilis.

Merih T Tesfazghi, Neil W Anderson, Ann M Gronowski, Melanie L Yarbrough

Open access · bronzeAbstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Brazilian Protocol for Sexually Transmitted Infections 2020: syphilis diagnostic tests.Revista da Sociedade Brasileira de Medicina Tropical · 2021
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Merih T TesfazghiDepartment of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Neil W AndersonDepartment of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Ann M GronowskiDepartment of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Melanie L YarbroughDepartment of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA myarbro@wustl.edu.ORCID 0000-0003-2166-7552
Washington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Manual treponemal and nontreponemal serologic testing has historically been used for the diagnosis of syphilis. This approach is simple and reproducible but labor intensive. Recently, the FDA cleared the fully automated BioPlex 2200 Syphilis Total & RPR assay for the detection of treponemal and nontreponemal antibodies. We evaluated the clinical performance of this assay at a tertiary medical center with a high syphilis prevalence. Prospective consecutively collected (

Indexed as

Immunoenzyme TechniquesAdolescentAdultAgedAged, 80 and overAlgorithmsAntibodies, BacterialAutomation, LaboratoryChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMass ScreeningAntibodies, BacterialReagent Kits, DiagnosticReaginsBioPlexFTARPRsyphilistraditional algorithm

Identifiers

PMID30429251
PMCPMC6322462
OpenAlexW2899546438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.