Evidence map›Paper›PMID 30429210›Full record

ArticleMolecular & cellular proteomics : MCP2019

Identification of TEX101-associated Proteins Through Proteomic Measurement of Human Spermatozoa Homozygous for the Missense Variant rs35033974.

Christina Schiza, Dimitrios Korbakis, Keith Jarvi, Eleftherios P Diamandis, Andrei P Drabovich

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Christina SchizaDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;; Department of Pathology and Laboratory Medicine.
Dimitrios KorbakisDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;; Lunenfeld-Tanenbaum Research Institute.
Keith JarviLunenfeld-Tanenbaum Research Institute,; Department of Surgery, Division of Urology, Mount Sinai Hospital, Toronto, Canada.
Eleftherios P DiamandisDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;; Department of Pathology and Laboratory Medicine,; Lunenfeld-Tanenbaum Research Institute,; Department of Clinical Biochemistry, University Health Network, Toronto, Canada. Electronic address: eleftherios.diamandis@sinaihealthsystem.ca.
Andrei P DrabovichDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;; Department of Pathology and Laboratory Medicine,; Department of Clinical Biochemistry, University Health Network, Toronto, Canada. Electronic address: andrei.drabovich@ualberta.ca.
University Health Network · CAUniversity of Toronto · CAMount Sinai Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TEX101 is a germ-cell-specific protein and a validated biomarker of male infertility. Mouse TEX101 was found essential for male fertility and was suggested to function as a cell surface chaperone involved in maturation of proteins required for sperm migration and sperm-oocyte interaction. However, the precise functional role of human TEX101 is not known and cannot be studied

Indexed as

Mutation, MissenseDown-RegulationGene Expression RegulationHomozygoteHumansInfertility, MaleMaleMembrane ProteinsProtein Interaction MapsProteolysisProteomicsSemenSpermatozoaMembrane ProteinsTEX101 protein, humanClinical ProteomicsImmunoaffinityLabel-free QuantificationParallel Reaction MonitoringProtein IdentificationProteogenomicsrs35033974Selected Reaction MonitoringSingle Nucleotide VariantSpermatozoaTestis-specific ProteinsTEX10

Identifiers

PMID30429210
PMCPMC6356071
OpenAlexW2900768108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.