ArticleBlood2019
The
Abstract read
In one paragraph
Article in Blood, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk.Blood · 2024Pooled it
- Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas.Circulation research · 2020Pooled it
- Article
- miR-499 in Platelet-Derived Extracellular Vesicles Augments Inflammatory Cell Generation and Cardiac Remodeling After Myocardial Infarction.Circulation · 2026Article
- A guide to cell-type-specific Cre mouse models in atherosclerosis: from background strains to future directions.Frontiers in cardiovascular medicine · 2026Review
- Synergistic effects of deleting the tyrosine phosphatases Shp1 and Shp2 on megakaryopoiesis and thrombopoiesis in mice.bioRxiv : the preprint server for biology · 2025Article
- Platelet-specific SLFN14 deletion causes macrothrombocytopenia and platelet dysfunction through dysregulated megakaryocyte and platelet gene expression.The Journal of clinical investigation · 2025Article
- Deleting ACC1 in platelets alters phospholipidome and reduces platelet activation and thrombosis in mice.Blood advances · 2025Article
- Distinct platelet transcriptomic heterogeneity in respiratory illnesses and modulation by corticosteroids and immune antibody treatments.Journal of translational medicine · 2025Article
- Pattern recognition receptor-associated immuno-thrombotic transcript changes in platelets and leukocytes with COVID19.PLoS pathogens · 2025Article
- Histone lysine methyltransferases MLL3 and MLL4 direct gene expression to produce platelets efficiently.Nature communications · 2025Article
- Pathogenic strains of a gut commensal drive systemic platelet activation and thromboinflammation in lupus nephritis.bioRxiv : the preprint server for biology · 2025Article
- CD40-TRAF6 inhibition suppresses cardiovascular inflammation, oxidative stress and functional complications in a mouse model of arterial hypertension.Redox biology · 2025Article
- Reply to Chong et al.: Investigating TGFβ1 biological activities using genetically engineered mouse strains.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The small noncoding RNARNA (New York, N.Y.) · 2024Article
- Aging-related alterations in mechanistic target of rapamycin signaling promote platelet hyperreactivity and thrombosis.Journal of thrombosis and haemostasis : JTH · 2024Article
- The small non-coding RNAbioRxiv : the preprint server for biology · 2024Article
- Differential Impact In Vivo of Pf4-ΔCre-Mediated and Gp1ba-ΔCre-Mediated Depletion of Cyclooxygenase-1 in Platelets in Mice.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
- Review
- Platelet-derived thrombospondin 1 promotes immune cell liver infiltration and exacerbates diet-induced steatohepatitis.JHEP reports : innovation in hepatology · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Zoltan NagyInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0001-6517-2071
Timo VögtleInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Mitchell J GeerInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0003-1457-987X
Jun MoriInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Silke HeisingInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Giada Di NunzioInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Ralph GareusThe Jackson Laboratory, Bar Harbor, ME.
Alexander TarakhovskyLaboratory of Immune Cell Epigenetics and Signaling, The Rockefeller University, New York, NY.
Arthur WeissDivision of Rheumatology, Rosalind Russell and Ephraim P. Engleman Rheumatology Research Center and Howard Hughes Medical Institute, University of California, San Francisco, CA.
Benjamin G NeelLaura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY; and.
Guillaume E DesantiInstitute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0003-4902-1868
Alexandra MazharianInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Yotis A SenisInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0002-0947-9957
Funding
NHLBI CLINICAL INVESTIGATOR AWARD PROGRAMK08HL001513 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI UDERMAN, HOWARD · 1985 to 1986
–British Heart Foundation FS/13/1/29894British Heart Foundation FS/15/58/31784Medical Research Council GBT1564
Abstract
Conditional knockout (KO) mouse models are invaluable for elucidating the physiological roles of platelets. The
Indexed as
AgglutinationAnimalsBlood PlateletsBone Marrow CellsCell LineageCell SizeCSK Tyrosine-Protein KinaseGene TargetingHomeostasisIntegrasesLeukocytesLymphocyte CountMegakaryocytesMice, Inbred C57BLMice, TransgenicModels, Animaladhesion receptorCre recombinaseCSK Tyrosine-Protein KinaseIntegrasesPlatelet Factor 4Platelet Glycoprotein GPIb-IX ComplexPtprj protein, mouseReceptor-Like Protein Tyrosine Phosphatases, Class 3src-Family Kinases
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.