Evidence map›Paper›PMID 30428917›Full record

ArticleBMC research notes2018

Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru.

Miguel Angel Aguilar-Luis, Fernando Palacios-Cuervo, Fátima Espinal-Reyes, Andrea Calderón-Rivera, Saúl Levy-Blitchtein, Carlos Palomares-Reyes, Wilmer Silva-Caso, Victor Zavaleta-Gavidia, Jorge Bazán-Mayra, Angela Cornejo-Tapia and 2 more

Abstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Global Profile of Drug Resistance Related toHealth science reports · 2025
    Review
  2. Article
  3. Article
  4. Antimicrobial susceptibility of clinicalMicrobiology spectrum · 2024
    Article
  5. Article
  6. Current Worldwide Trends in PediatricChildren (Basel, Switzerland) · 2023
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Miguel Angel Aguilar-LuisSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru.
Fernando Palacios-CuervoSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru.
Fátima Espinal-ReyesSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru.
Andrea Calderón-RiveraSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru.
Saúl Levy-BlitchteinSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru.
Carlos Palomares-ReyesLaboratorio de Biología Molecular, Instituto de Investigación Nutricional, Lima, Peru.
Wilmer Silva-CasoSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru.
Victor Zavaleta-GavidiaDirección Regional de Salud de Cajamarca (DIRESA-Cajamarca), Cajamarca, Peru.
Jorge Bazán-MayraDirección Regional de Salud de Cajamarca (DIRESA-Cajamarca), Cajamarca, Peru.
Angela Cornejo-TapiaSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru.
Juana Del Valle-MendozaSchool of Medicine, Research and Innovation Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Av. San marcos Cdra 2, Chorrillos, Lima, Peru. juana.delvalle@upc.pe.ORCID http://orcid.org/0000-0002-6011-5040
Luis J Del ValleBarcelona Research Center for Multiscale Science and Engineering, Departament d'Enginyeria Química, EEBE, Universidad Politecnica de Catalunya (UPC), Barcelona Tech, Barcelona, Spain. luis.javier.del.valle@upc.edu.

Funding

4th Incentive for Research of the Universidad Peruana de Ciencias Aplicadas. Grant:UPC-EXP 004-2016. Lima-Peru.
6 · The paper itself

Abstract

objectiveThe objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru).

resultsHelicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G-A2143G (28.6%).

Indexed as

AdolescentAnti-Bacterial AgentsChildClarithromycinCross-Sectional StudiesDrug Resistance, BacterialFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMutationPeruPrevalenceRNA, Ribosomal, 23SRural PopulationAnti-Bacterial AgentsClarithromycinRNA, Ribosomal, 23SClarithromycinGastric diseaseHelicobacter pyloriPCRPeptic ulcer disease

Identifiers

PMID30428917
PMCPMC6236992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.