Evidence map›Paper›PMID 30428890›Full record

Trial reportEnvironmental health : a global access science source2018

Particulate matter exposure and health impacts of urban cyclists: a randomized crossover study.

Christie A Cole, Christopher Carlsten, Michael Koehle, Michael Brauer

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Environmental health : a global access science source, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01708356 (Cycling, Air Pollution and Health), which is not on this map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01708356 nacompletednot on this map

Cycling, Air Pollution and Health

TypeinterventionalSponsorUniversity of British ColumbiaRan2010 to 2011Enrolled38ConditionsEndothelial Dysfunction, Endothelial Function, Cardiovascular Physiological PhenomenaArmsCycling on a residential route
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Environmental and Occupational Short-Term Exposure to Airborne Particles and FEVInternational journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Trial
  5. A computational framework for agent-based assessment of multiple environmental exposures.Journal of exposure science & environmental epidemiology · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christie A ColeSchool of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada.
Christopher CarlstenAir Pollution Exposure Lab, Department of Medicine, University of British Columbia, 2775 Laurel Street 7th Floor, Vancouver, BC, V5Z 1M9, Canada.
Michael KoehleSchool of Kinesiology and Division of Sport & Exercise Medicine, University of British Columbia, 2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada.
Michael BrauerSchool of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada. michael.brauer@ubc.ca.ORCID 0000-0002-9103-9343
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCycling and other forms of active transportation provide health benefits via increased physical activity. However, direct evidence of the extent to which these benefits may be offset by exposure and intake of traffic-related air pollution is limited. The purpose of this study is to measure changes in endothelial function, measures of oxidative stress and inflammation, and lung function in healthy participants before and after cycling along a high- and low- traffic route.

methodsParticipants (n = 38) bicycled for 1 h along a Downtown and a Residential designated bicycle route in a randomized crossover trial. Heart rate, power output, particulate matter air pollution (PM

resultsGeometric mean PNC exposures and intakes were higher along the Downtown (exposure = 16,226 particles/cm

conclusionsAlthough PNC exposures and intakes were higher along the Downtown route, the lack of association between air pollutant exposure or intake with RHI and other measures suggests other exposures related to cycling on the Downtown route may have been influential in the observed differences between routes in RHI.

trial registrationClinicalTrials.gov, NCT01708356 . Registered 16 October 2012.

Indexed as

Bicycling8-Hydroxy-2'-DeoxyguanosineAdultAir PollutantsBritish ColumbiaCitiesC-Reactive ProteinCross-Over StudiesDeoxyguanosineEnvironmental ExposureFemaleHumansInterleukin-6MaleParticulate MatterRespiratory Function Tests8-Hydroxy-2'-DeoxyguanosineAir PollutantsC-Reactive ProteinDeoxyguanosineIL6 protein, humanInterleukin-6Particulate MatterAir pollutionCyclingEndothelial functionInflammationLung functionOxidative stressParticulate matter

Identifiers

PMID30428890
PMCPMC6237024
OpenAlexW2901799076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.