Evidence map›Paper›PMID 30428870›Full record

ArticleBMC surgery2018

Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report.

Ma Luisa Villalón, Ma De Los Ángeles Leal, José R Chávez, Eduardo M Santillán, Ismael Lares-Asseff, Verónica Loera, Laura Valencia, Blanca Camacho, Brenda Alvarado, Vilma Cervantes and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ma Luisa VillalónThe Californias' Children Hospital Ophthalmology Service, Av. Alejandro Von Humboldt 11431, Garita de Otay, 22509, Tijuana, BC, Mexico.
Ma De Los Ángeles LealSchool of Health Sciences, Valle de Las Palmas, Autonomous University of Baja California, Blvd Universitario 1000, Valle de Las Palmas, 22260, Tijuana, BC, Mexico.
José R ChávezSchool of Health Sciences, Valle de Las Palmas, Autonomous University of Baja California, Blvd Universitario 1000, Valle de Las Palmas, 22260, Tijuana, BC, Mexico.
Eduardo M SantillánFray Junípero Serra Hospital, Security and Social Services Institute for State Workers, Tijuana, Avenida De Las Palmas 1 Col Las Palmas, 22106, Tijuana, BC, Mexico.
Ismael Lares-AsseffInterdisciplinary Research Center for the Comprehensive Regional Development, Durango Module, Durango, Mexico.
Verónica LoeraInterdisciplinary Research Center for the Comprehensive Regional Development, Durango Module, Durango, Mexico.
Laura ValenciaDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.
Blanca CamachoDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.
Brenda AlvaradoDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.
Vilma CervantesDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.
Leslie PatrónDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.
Horacio AlmanzaDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico. almanzareyes@uabc.edu.mx.ORCID http://orcid.org/0000-0002-1874-3975
Universidad Autónoma de Baja California · MXDurango Institute of Technology · MX

Funding

Targeting protein-protein interactions of Bmi1 oncoproteinR01CA201204 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GREMBECKA, JOLANTA · 2016 to 2018
$959k
Consejo Nacional de Ciencia y Tecnología 2013-1-201204
6 · The paper itself

Abstract

backgroundThe dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. To our knowledge, this is the first described case of a patient with resection of dermoid cyst treated with human amniotic membrane implant and topical application of 0.02% mitomycin C. CASE PRESENTATION: We present a case of a 12-year-old male with a tumour in the superotemporal region of the right eye (RE). Symptoms included decreased visual acuity (VA), burning eye, foreign body sensation, and photophobia of the affected eye. A physical examination detected blepharospasm. Ophthalmic examination of his RE, fingers count from a 1-2 m distance, showed no improvement with pinhole. Visual acuity was 20/20 on the left eye (LE). The bio-microscopic examination confirmed the presence of a tumour mass (15 mm × 12 mm) on the surface of the RE, invading the superotemporal sector. The tumour had a lobulated appearance, a shiny and vascularized surface covered by conjunctiva, a pearlescent-pink colour, a medium consistency, was renitent and painless. An ultrasound scan revealed atrophy of the pigmented retinal epithelium with scleral indentation of the RE. A computed tomography (CT) scan revealed a recurrent lesion consistent with an epibulbar dermoid cyst. Surgical excision of the lesion was performed and a human amniotic membrane (HAM) graft and topical 0.02% mitomycin C (MMC) were applied. Histopathological analysis confirmed the diagnosis of recurrent dermoid cyst.

conclusionIn this case report, we describe a case of recurrent epibulbar dermoid cyst treated with complete resection; topical MMC and HAM implant with good clinical outcome of the lesion and implant adhesion. Resection of a cyst of the ocular surface is not recommended when a large epibulbar dermoid tissue needs to be resected and no HAM graft is available.

Indexed as

AmnionChildDermoid CystHumansMaleOrbital NeoplasmsTomography, X-Ray ComputedUltrasonographyAmniotic membraneDermoid cystMitomycin c

Identifiers

PMID30428870
PMCPMC6236942
OpenAlexW2901393486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.