ArticleBMC infectious diseases2018
Analysis of sero-epidemiological characteristics of varicella in healthy children in Jiangsu Province, China.
Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 17 citations in OpenAlex.
- A Cross-Sectional Seroepidemiological Study on Varicella Zoster Virus in Zhejiang, China.Vaccines · 2026Article
- Effectiveness of varicella vaccine during a varicella outbreak in a Chinese senior high school: a retrospective cohort study.Frontiers in immunology · 2026Article
- Epidemiological Characteristics and Spatiotemporal Clustering of Varicella in the Border City of Baise, Southwest China, 2010-2024.Infection and drug resistance · 2026Article
- Seroepidemiological survey of the population 10 years after the implementation of the varicella vaccine 2-dose immunization strategy.Human vaccines & immunotherapeutics · 2025Article
- Analysis and comparison of chickenpox outbreaks in two schools at different educational stages: a mixed retrospective observational study.BMC infectious diseases · 2025Observational
- A Spatial analysis of chickenpox in Chongqing, China, during 2015-2023.Scientific reports · 2025Article
- Impact of natural and socio-economic factors on varicella incidence in children in Shanghai, 2013-2022.Frontiers in public health · 2025Article
- Analysis of sero-epidemiological characteristics of varicella in healthy children in Wuxi, China.Human vaccines & immunotherapeutics · 2024Article
- Surveillance of adverse events following varicella vaccine immunization in Jiangsu province, China from 2017 to 2023.BMC infectious diseases · 2024Article
- Seroprevalence rates in children aged 3-6 years after implementing a two-dose varicella vaccination: A observational study.Human vaccines & immunotherapeutics · 2023Observational
- Analysis on the epidemiological characteristics of varicella and breakthrough case from 2014 to 2022 in Qingyang City.Human vaccines & immunotherapeutics · 2023Article
- Article
- Assessing vaccine effectiveness for varicella in Wuxi, China: a time-series analysis.Annals of medicine · 2023Article
- Effectiveness of one-dose versus two-dose varicella vaccine in children in Qingdao, China: a matched case-control study.Human vaccines & immunotherapeutics · 2021Article
- One single-center cross-sectional investigation on varicella antibody level of all age groups in Chinese people.Human vaccines & immunotherapeutics · 2021Article
- Uptrend prevalence of varicella parallel with low serum antibodies and low second-dose rate among children 10-14 years old in Wenzhou, China.Human vaccines & immunotherapeutics · 2021Article
- Spatiotemporal Epidemiology of Varicella in Chongqing, China, 2014-2018.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundIn recent years, outbreaks of varicella have continued to occur, and the coverage rate of varicella vaccine in Jiangsu Province, China, remains unclear. This study aims to analyse the levels of immune antibody against varicella and obtain a comprehensive understanding of the varicella attenuated live vaccine (VarV) coverage rate in children aged 1-9 years in Jiangsu Province.
methodsFrom June to October 2016, a cross-sectional survey was conducted to collect 3631 serum samples from healthy children aged 1-9 years in Jiangsu Province. The immunoglobulin G (IgG) antibody levels of varicella were detected by enzyme-linked immunosorbent assay (ELISA).
resultsThe VarV coverage rate of healthy children was only 43.1% (95% CI: 41.1-44.7%). The seroprevalence after vaccination with a single dose of VarV was only 57.1%, and the overall seropositivity and geometric antibody titre (GMC) were 43.5% and 225.4 mU/ml, respectively. The seropositivity was significantly higher in girls than in boys (χ
conclusionThe VarV coverage rate of healthy children in Jiangsu Province was low. Sero-conversion rates were also low after one dose of VarV, and the immune effectiveness of a single dose of VarV was limited. To control the spread of varicella, VarV should be included in the routine immunization program, and strengthened immunization measures for the varicella-susceptible population warrant additional consideration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.