Evidence map›Paper›PMID 30428842›Full record

ArticleBMC microbiology2018

Characteristics of NDM-1-producing Klebsiella pneumoniae ST234 and ST1412 isolates spread in a neonatal unit.

Xu Huang, Xiangjun Cheng, Pengfei Sun, Chenjie Tang, Fang Ni, Genyan Liu

Abstract read
In one paragraph

Article in BMC microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Two Phenotypes ofInfection and drug resistance · 2022
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  11. Emergence of a NDM-1-producing ST25Frontiers in microbiology · 2022
    Article
  12. Article
  13. Review
  14. Genomics and Virulence ofMicroorganisms · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Characterization OfInfection and drug resistance · 2019
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xu HuangDepartment of Laboratory Medicine, the First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Xiangjun ChengDepartment of Laboratory Medicine, the First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Pengfei SunDepartment of Laboratory Medicine, the First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Chenjie TangDepartment of Laboratory Medicine, the First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Fang NiDepartment of Laboratory Medicine, the First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Genyan LiuDepartment of Laboratory Medicine, the First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People's Republic of China. liugenyan@jsph.org.cn.ORCID 0000-0002-1004-2517

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence of carbapenem-resistant Klebsiella pneumoniae (CR-KP) has become a significant problem worldwide and also being a major threat to children and newborns. Here we report an outbreak of NDM-1-producing K. pneumoniae in a neonatal unit.

resultsSix CR-KP strains, isolated from neonates with symptoms of infection, were identified using a VITEK-2 compact system, and the clinical data were retrieved from the electronic case records. In vitro susceptibility testing with broth dilution method showed that all six K. pneumoniae isolates were resistant to carbapenems and susceptible to colistin, aminoglycosides, fluoroquinolones and tigecycline. Based on the polymerase chain reaction results, each isolate was found to be bla

conclusionsST234 and ST1412 of NDM-1-producing Klebsiella pneumoniae are the resistant clone spread in the neonatal unit, comprehensive infection control measures and optimized carbapenem therapy played an important role in controlling this NDM-1-producing K. pneumoniae outbreak.

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCross InfectionDisease OutbreaksFemaleHumansInfantKlebsiella InfectionsKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMultilocus Sequence TypingAnti-Bacterial AgentsBacterial Proteinsbeta-lactamase NDM-1beta-Lactamasesbla NDM-1Multidrug-Resistant, carbapenem-resistant Klebsiella pneumoniaeNeonateOutbreak

Identifiers

PMID30428842
PMCPMC6234558

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.