ArticleThe Korean journal of internal medicine2019
Association between blood pressure, inflammation and spirometry parameters in chronic obstructive pulmonary disease.
Article in The Korean journal of internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Association of Coexisting Hypertension and Diabetes with Blood Gas Analysis Indicators in COPD Patients: A Propensity Score-Matched Analysis.Healthcare (Basel, Switzerland) · 2026Article
- Association of cardiac autonomic functions with inflammatory markers in chronic obstructive pulmonary disease.Journal of family medicine and primary care · 2025Article
- Nurse Staffing Management in the Context of Emergency Departments and Seasonal Respiratory Diseases: An Artificial Intelligence and Discrete-Event Simulation Approach.Journal of medical systems · 2025Article
- Effect of plasma free fatty acids on lung function in male COPD patients.Scientific reports · 2025Article
- Causal Associations Between Chronic Obstructive Pulmonary Disease and Common Comorbidities: Evidence from Comprehensive Genetic Methods.International journal of chronic obstructive pulmonary disease · 2025Article
- Low Life Essential 8 Score as a Risk Factor for Long-Term Mortality in Chronic Obstructive Pulmonary Disease: A Study Based on the Analysis of NHANES Data from 2007 to 2012.International journal of chronic obstructive pulmonary disease · 2024Article
- Using random forest machine learning on data from a large, representative cohort of the general population improves clinical spirometry references.The clinical respiratory journal · 2023Article
- Forecast the Exacerbation in Patients of Chronic Obstructive Pulmonary Disease with Clinical Indicators Using Machine Learning Techniques.Diagnostics (Basel, Switzerland) · 2021Article
- Low Vitamin D Status Is Associated with Inflammation in Patients with Chronic Obstructive Pulmonary Disease.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsMany systems including the cardiovascular system (ischemic heart diseases, heart failure, and hypertension) may act as comorbidities that can be seen during the course of chronic obstructive pulmonary disease (COPD). Comorbidities affect the severity and prognosis of COPD negatively. Nearly 25% of patients with COPD die due to cardiovascular diseases. In this study, we aimed to evaluate the relationship between the blood pressure, inflammation, hypoxia, hypercapnia, and the severity of airway obstruction.
methodsWe included 75 COPD patients in the study with 45 control cases. We evaluated age, sex, body mass index, smoking history, C-reactive protein levels, 24-hour ambulatory blood pressure Holter monitoring, arterial blood gas, and respiratory function tests of the patient and the control groups.
resultsIn COPD patients, the night time systolic, diastolic blood pressures and pulse per minute and the mean blood pressures readings were significantly elevated compared to the control group (p < 0.05). In the correlation analysis, night time systolic pressure was associated with all the parameters except forced expiratory volume in 1 second (FEV1%). Diastolic blood pressure was associated with pH and HCO3 levels. The mean night time, day time pulse pressures and 24- hour pulse per minute values were also associated with all the parameters except FEV1%.
conclusionIn this study we found that parameters of systolic and diastolic blood pressures and pulse pressures were significantly elevated in COPD patients compared to the control groups. Blood pressure was associated blood gas parameters and inflammation parameters in COPD patients. This, in turn, may cause understanding of the pathophysiology of COPD and its complications.
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