Evidence map›Paper›PMID 30428636›Full record

ArticleMolecules (Basel, Switzerland)2018

Crystallographic and Computational Characterization of Methyl Tetrel Bonding in S-Adenosylmethionine-Dependent Methyltransferases.

Raymond C Trievel, Steve Scheiner

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 40 citations in OpenAlex.

  1. Interaction of Lead(II) Perchlorate withInorganic chemistry · 2025
    Article
  2. Taxonomy of Chemical Bondings: Opportunities and Challenges.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Methyl transfer in psilocybin biosynthesis.Nature communications · 2024
    Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Raymond C TrievelDepartment of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. rtrievel@umich.edu.
Steve ScheinerDepartment of Chemistry and Biochemistry, Utah State University, Logan, UT 84322, USA. steve.scheiner@usu.edu.ORCID 0000-0003-0793-0369
University of Michigan · USUtah State University · US

Funding

National Science Foundation CHE-1508492
6 · The paper itself

Abstract

Tetrel bonds represent a category of non-bonding interaction wherein an electronegative atom donates a lone pair of electrons into the sigma antibonding orbital of an atom in the carbon group of the periodic table. Prior computational studies have implicated tetrel bonding in the stabilization of a preliminary state that precedes the transition state in S

Indexed as

Models, MolecularCrystallographyHydrogen BondingMethyltransferasesMolecular ConformationMolecular StructureQuantum TheoryS-AdenosylmethionineStructure-Activity RelationshipMethyltransferasesS-AdenosylmethionineAdoMetcharge transfermethylationmethyl transfermethyltransferasemolecular electrostatic potentialnoncovalent bondS-adenosylmethionineSAMsigma-holeSN2 reactiontetrel bond

Identifiers

PMID30428636
PMCPMC6278250
OpenAlexW2900586228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.