Evidence map›Paper›PMID 30428554›Full record

ArticleMicromachines2018

Cell Injection Millirobot Development and Evaluation in Microfluidic Chip.

Lin Feng, Qiang Zhou, Bin Song, Yanmin Feng, Jun Cai, Yonggang Jiang, Deyuan Zhang

Abstract read
In one paragraph

Article in Micromachines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lin FengSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. linfeng@buaa.edu.cn.ORCID 0000-0002-5158-3862
Qiang ZhouSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. zhqiang1996@163.com.
Bin SongSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. songb@buaa.edu.cn.
Yanmin FengSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. feng_yan_min202@126.com.
Jun CaiSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. jun_cai@buaa.edu.cn.
Yonggang JiangSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. jiangyg@buaa.edu.cn.ORCID 0000-0003-1979-996X
Deyuan ZhangSchool of Mechanical Engineering & Automation, Beihang University, Beijing 100191, China. zhangdy@buaa.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose an innovative design of millirobot, which can achieve donor cell suction, delivery, and injection in a mammalian oocyte on a microfluidic chip. The millirobot body contains a hollow space that produces suction and ejection forces for the injection of cell nuclei using a nozzle at the tip of the robot. Specifically, a controller changes the hollow volume by balancing the magnetic and elastic forces of a membrane along with the motion of stages in the XY plane. A glass capillary attached to the tip of the robot contains a nozzle that is able to absorb and inject cell nuclei. The millirobot provides three degrees of freedom and generates micronewton forces. We demonstrate the effectiveness of the proposed millirobot through an experiment of the absorption and ejection of 20-µm particles from the nozzle using magnetic control in a microfluidic chip.

Indexed as

cell nucleuscell surgeryinjectionmagnetic controlmillirobot

Identifiers

PMID30428554
PMCPMC6266326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.