ArticleiScience2018
Leptosphaeria maculans Effector Protein AvrLm1 Modulates Plant Immunity by Enhancing MAP Kinase 9 Phosphorylation.
Article in iScience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 101 citations in OpenAlex.
- Location and timing govern tripartite interactions of fungal phytopathogens and host in the stem canker species complex.BMC biology · 2023Article
- Insights on Novel Effectors and Characterization of Metacaspase (RS107_6) as a Potential Cell Death-Inducing Protein inMicroorganisms · 2023Article
- Identification of candidate genes forFrontiers in plant science · 2023Article
- Predicting Cloned Disease Resistance Gene Homologs (CDRHs) in Radish, Underutilised Oilseeds, and Wild Brassicaceae Species.Plants (Basel, Switzerland) · 2022Article
- Fungal Effectoromics: A World in Constant Evolution.International journal of molecular sciences · 2022Review
- Microbial Effectors: Key Determinants in Plant Health and Disease.Microorganisms · 2022Review
- A serine-rich effector from the stripe rust pathogen targets a Raf-like kinase to suppress host immunity.Plant physiology · 2022Article
- Transcriptome Analysis of Fusarium-Tomato Interaction Based on an Updated Genome Annotation ofJournal of fungi (Basel, Switzerland) · 2022Article
- Article
- Nicotiana benthamiana asparagine synthetase associates with IP-L and confers resistance against tobacco mosaic virus via the asparagine-induced salicylic acid signalling pathway.Molecular plant pathology · 2022Article
- Large-scale transcriptomics to dissect 2 years of the life of a fungal phytopathogen interacting with its host plant.BMC biology · 2021Article
- Wheat Apoplast-Localized Lipid Transfer ProteinFrontiers in plant science · 2021Article
- Recent Findings Unravel Genes and Genetic Factors UnderlyingInternational journal of molecular sciences · 2020Review
- The Brassica napus wall-associated kinase-like (WAKL) gene Rlm9 provides race-specific blackleg resistance.The Plant journal : for cell and molecular biology · 2020Article
- Understanding Host-Pathogen Interactions inPlants (Basel, Switzerland) · 2020Review
- Proteinaceous effector discovery and characterization in filamentous plant pathogens.Molecular plant pathology · 2020Review
- All Roads Lead to Susceptibility: The Many Modes of Action of Fungal and Oomycete Intracellular Effectors.Plant communications · 2020Review
- TaTLP1 interacts with TaPR1 to contribute to wheat defense responses to leaf rust fungus.PLoS genetics · 2020Article
- Arms race: diverse effector proteins with conserved motifs.Plant signaling & behavior · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptosphaeria maculans, the causal agent of blackleg disease in canola (Brassica napus), secretes an array of effectors into the host to overcome host defense. Here we present evidence that the L. maculans effector protein AvrLm1 functions as a virulence factor by interacting with the B. napus mitogen-activated protein (MAP) kinase 9 (BnMPK9), resulting in increased accumulation and enhanced phosphorylation of the host protein. Transient expression of BnMPK9 in Nicotiana benthamiana induces cell death, and this phenotype is enhanced in the presence of AvrLm1, suggesting that induction of cell death due to enhanced accumulation and phosphorylation of BnMPK9 by AvrLm1 supports the initiation of necrotrophic phase of L. maculans infection. Stable expression of BnMPK9 in B. napus perturbs hormone signaling, notably salicylic acid response genes, to facilitate L. maculans infection. Our findings provide evidence that a MAP kinase is directly targeted by a fungal effector to modulate plant immunity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.