ArticlePloS one2018
Overexpression of BcHsfA1 transcription factor from Brassica campestris improved heat tolerance of transgenic tobacco.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Abiotic Stress in Crop Production.International journal of molecular sciences · 2023Pooled it
- Genome-wide identification and expression analysis of heat shock factors in Plantago fengdouensis under abiotic stresses.BMC plant biology · 2026Article
- Identification of HSF gene family and functional analysis of two HSFA1 genes with tandem repeat features in Fritillaria cirrhosa D.Don.BMC genomics · 2026Article
- A Heat-Shock Transcription Factor inInternational journal of molecular sciences · 2025Article
- Exogenous treatment with N-acetylglutamic acid confers tolerance to heat stress in plants.Plant biotechnology (Tokyo, Japan) · 2024Article
- Tobacco production under global climate change: combined effects of heat and drought stress and coping strategies.Frontiers in plant science · 2024Review
- Genome-wide analysis of HSF family and overexpression ofFrontiers in plant science · 2023Article
- Mechanisms of Kale (International journal of molecular sciences · 2022Article
- Molecular insights into sensing, regulation and improving of heat tolerance in plants.Plant cell reports · 2022Review
- Adaptation Strategies to Improve the Resistance of Oilseed Crops to Heat Stress Under a Changing Climate: An Overview.Frontiers in plant science · 2021Review
- Review
- Heat stress inducible cytoplasmic isoform of ClpB1 from Z. nummularia exhibits enhanced thermotolerance in transgenic tobacco.Molecular biology reports · 2020Article
- Heat shock protein 70 (HmHsp70) from Hypsizygus marmoreus confers thermotolerance to tobacco.AMB Express · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat shock proteins (HSPs) are a type of conserved molecular chaperone. They exist extensively in plants and greatly contribute to their survival under heat stress. The transcriptional regulation factor heat shock factor (HSF) is thought to regulate the expression of Hsps. In this study, a novel gene designated BcHsfA1 was cloned and characterized from Brassica campestris. Bioinformatic analysis implied that BcHsfA1 belongs to the HsfA gene family and is most closely related to HsfA1 from other plants. Constitutive overexpression of BcHsfA1 significantly improved heat tolerance of tobacco seedlings by affecting physiological and biochemical processes. Moreover, the chlorophyll content of transgenic tobacco plants was significantly increased compared with wild type after heat stress, as were the activities of the important enzymatic antioxidants superoxide dismutase and peroxidase. BcHsfA1 overexpression also resulted in decreased malondialdehyde content and comparative electrical conductivity and increased soluble sugar content in transgenic tobacco plants than wild-type plants exposed to heat stress. Furthermore, we identified 11 candidate heat response genes that were significantly up-regulated in the transgenic lines exposed to heat stress. Together, these results suggested that BcHsfA1 is effective in improving heat tolerance of tobacco seedlings, which may be useful in the development of new heat-resisitant B. campestris strains by genetic engineering.
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