ArticlePloS one2018
Repeatability and predictive value of lactate threshold concepts in endurance sports.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07484776 (Metabolic Flexibility in Patients With Early Triple-negative Breast Cancer and the Possible Effect of a Physical Exercise Intervention), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Metabolic Flexibility in Patients With Early Triple-negative Breast Cancer and the Possible Effect of a Physical Exercise Intervention
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Impact of Pre-exercise Hypohydration on Aerobic Exercise Performance, Peak Oxygen Consumption and Oxygen Consumption at Lactate Threshold: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- The influence of foot muscles exercises and minimalist shoes on lactate threshold velocity in long-distance amateur runners: a randomized controlled trial.Scientific reports · 2024Trial
- Jumping on the moon as a potential exercise countermeasure.Experimental physiology · 2026Article
- Validation of a novel handheld lactate analyzer reveals concentration-dependent bias compared with a laboratory reference device.Biology open · 2026Article
- Validation of muscle oxygenation kinetics to predict aerobic fitness and exercise transition thresholds.Experimental physiology · 2026Article
- Defining the Heart Rate Zone Corresponding to the Lactate Threshold in Colombian Paso Horses.Animals : an open access journal from MDPI · 2025Article
- Power Output, Lactatemia, and Maximum Oxygen Consumption During a Specific Off-Water Incremental Test in International-Level Podium-Winner Kayak and Rowing Athletes.Journal of functional morphology and kinesiology · 2025Article
- Unaltered maximal power and submaximal performance correlates with an oxidative vastus lateralis proteome phenotype during tapering in male cyclists.Physiological reports · 2025Article
- Validity of smartwatch-derived estimates of lactate threshold heart rate and pace compared to graded exercise testing.Frontiers in physiology · 2025Article
- Strength gains and distinct acute blood lactate responses induced by stepwise load reduction training in healthy males.Frontiers in physiology · 2025Article
- Exercise capacity of male and female national team athletes in canoe slalom.Frontiers in physiology · 2025Article
- Concepts of Lactate Metabolic Clearance Rate and Lactate Clamp for Metabolic Inquiry: A Mini-Review.Nutrients · 2023Review
- Proposed Protocol for Field Testing of Endurance Fitness of Young Labrador Retrievers.Methods and protocols · 2023Article
- Maximum Heart Rate- and Lactate Threshold-Based Low-Volume High-Intensity Interval Training Prescriptions Provide Similar Health Benefits in Metabolic Syndrome Patients.Healthcare (Basel, Switzerland) · 2023Article
- The Influence of Nutrition and Physical Activity on Exercise Performance after Mild COVID-19 Infection in Endurance Athletes-CESAR Study.Nutrients · 2022Article
- Premorbid beta blockade in sepsis is associated with a lower risk of a lactate concentration above the lactate threshold, a retrospective cohort study.Scientific reports · 2022Article
- Creatine Kinase and Myoglobin Plasma Levels in Mountain Bike and Road Cyclists 1 h after the Race.International journal of environmental research and public health · 2022Article
- Impact of body fat, body water content, and skeletal muscle mass index on peak salivary lactate levels after squat jump exercise in healthy non-athlete adult males.BMC sports science, medicine & rehabilitation · 2022Article
- Relationships Between Maximal Aerobic Speed, Lactate Threshold, and Double Poling Velocity at Lactate Threshold in Cross-Country Skiers.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBlood lactate concentration rises exponentially during graded exercise when muscles produce more lactate than the body can remove, and the blood lactate-related thresholds are parameters based on this curve used to evaluate performance level and help athletes optimize training. Many different concepts of describing such a threshold have been published. This study aims to compare concepts for their repeatability and predictive properties of endurance performance.
methodsForty-eight well-trained male cyclists aged 18-50 performed 5 maximal graded exercise tests each separated by two weeks. Blood lactate-related thresholds were calculated using eight different representative concepts. Repeatability of each concept was assessed using Cronbach's alpha and intra-subject CV and predictive value with 45 minute time trial tests and a road race to the top of Mont Ventoux was evaluated using Pearson correlations.
resultsRepeatability of all concepts was good to excellent (Cronbach's alpha of 0.89-0.96), intra-subject CVs were low with 3.4-8.1%. Predictive value for performance in the time trial tests and road race showed significant correlations ranging from 0.65-0.94 and 0.53-0.76, respectively.
conclusionAll evaluated concepts performed adequate, but there were differences between concepts. One concept had both the highest repeatability and the highest predictability of cycling performance, and is therefore recommended to be used: the Dmax modified method. As an easier to apply alternative, the lactate threshold with a fixed value of 4 mmol/L could be used as it performed almost as well.
trial registrationDutch Trial Registry NTR5643.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.