Observational studyPloS one2018
Development and validation of an algorithm to predict the treatment modality of burn wounds using thermographic scans: Prospective cohort study.
Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03876340 (Impact of a Clinical Decision Algorithm on Length of Hospital Stay and Costs of Care of Burned Patients), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of a Clinical Decision Algorithm on Length of Hospital Stay and Costs of Care of Burned Patients: a Pragmatic Clinical Trial
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Pooled it
- Use of Polylactic Acid Dermal Matrix for the Management of Wounds with Exposed Avascular Structures.Journal of clinical medicine · 2025Article
- Facial Burn Healing With a Polylactic Acid Dermal Matrix: A Case Report on Wound Modulation and Graft-Free Epithelialization.Journal of burn care & research : official publication of the American Burn Association · 2025Article
- A Comprehensive Scoping Review on the Use of Point-Of-Care Infrared Thermography Devices for Assessing Various Wound Types.International wound journal · 2025Article
- Digital Infrared Thermographic Imaging for Limb Salvage in Patients at Risk of Amputation: Prospective Observational Study.JMIR formative research · 2025Observational
- Diabetic foot ulcer healing with polylactic acid membrane assessed by thermographic imaging: a case report.Frontiers in medicine · 2025Article
- Thermal imaging in biomedical research: a non-invasive technology for animal models.Frontiers in veterinary science · 2025Review
- Review of machine learning for optical imaging of burn wound severity assessment.Journal of biomedical optics · 2024Review
- Thermal Imaging as a Method to Indirectly Assess Peripheral Vascular Integrity and Tissue Viability in Veterinary Medicine: Animal Models and Clinical Applications.Animals : an open access journal from MDPI · 2023Review
- A Systematic Review of Artificial Intelligence Applications in Plastic Surgery: Looking to the Future.Plastic and reconstructive surgery. Global open · 2022Article
- The Use of Infrared Thermography (IRT) in Burns Depth Assessment: A Diagnostic Accuracy Meta-Analysis.European burn journal · 2022Review
- Use of Infrared Thermal Imaging for Assessing Acute Inflammatory Changes: A Case Series.Cureus · 2022Article
- Infrared Thermography in Wound Care, Surgery, and Sports Medicine: A Review.Frontiers in physiology · 2022Review
- Thermotropic Liquid Crystals for Temperature Mapping.Frontiers in bioengineering and biotechnology · 2022Article
- Machine Learning Demonstrates High Accuracy for Disease Diagnosis and Prognosis in Plastic Surgery.Plastic and reconstructive surgery. Global open · 2021Article
- Diagnostic accuracy of infrared thermal imaging for detecting COVID-19 infection in minimally symptomatic patients.European journal of clinical investigation · 2021Observational
- DL4Burn: Burn Surgical Candidacy Prediction using Multimodal Deep Learning.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2021Article
- Artificial intelligence in the management and treatment of burns: a systematic review.Burns & trauma · 2021Article
- Intrarater Reliability of Digital Thermography in Detecting Pin Site Infection: A Proof of Concept Study.Strategies in trauma and limb reconstructionArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe clinical evaluation of a burn wound alone may not be adequate to predict the severity of the injury nor to guide clinical decision making. Infrared thermography provides information about soft tissue viability and has previously been used to assess burn depth. The objective of this study was to determine if temperature differences in burns assessed by infrared thermography could be used predict the treatment modality of either healing by re-epithelization, requiring skin grafts, or requiring amputations, and to validate the clinical predication algorithm in an independent cohort. METHODS AND
findingsTemperature difference (ΔT) between injured and healthy skin were recorded within the first three days after injury in previously healthy burn patients. After discharge, the treatment modality was categorized as re-epithelization, skin graft or amputation. Potential confounding factors were assessed through multiple linear regression models, and a prediction algorithm based on the ΔT was developed using a predictive model using a recursive partitioning Random Forest machine learning algorithm. Finally, the prediction accuracy of the algorithm was compared in the development cohort and an independent validation cohort. Significant differences were found in the ΔT between treatment modality groups. The developed algorithm correctly predicts into which treatment category the patient will fall with 85.35% accuracy. Agreement between predicted and actual treatment for both cohorts was weighted kappa 90%.
conclusionInfrared thermograms obtained at first contact with a wounded patient can be used to accurately predict the definitive treatment modality for burn patients. This method can be used to rationalize treatment and streamline early wound closure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.