Evidence map›Paper›PMID 30427766›Full record

ReviewHuman vaccines & immunotherapeutics2019

Global impact of varicella vaccination programs.

Fernanda Hammes Varela, Leonardo Araújo Pinto, Marcelo Comerlato Scotta

Open access · bronzeAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 6 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 6 syntheses or guidelines pooled it, 168 citations in OpenAlex.

  1. Pooled it
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  4. Pediatric herpes zoster ophthalmicus: a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Article
  9. Article
  10. Review
  11. Article
  12. Varicella zoster virus infection.Nature reviews. Disease primers · 2026
    Review
  13. Article
  14. Article
  15. Article
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  17. Article
  18. Article
  19. Article
  20. Last mile at the center of immunization delivery.Frontiers in epidemiology · 2026
    Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fernanda Hammes Varelaa Centro Infant, Department of Pediatrics , School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) , Porto Alegre , Rio Grande do Sul state , Brazil.
Leonardo Araújo Pintoa Centro Infant, Department of Pediatrics , School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) , Porto Alegre , Rio Grande do Sul state , Brazil.
Marcelo Comerlato Scottaa Centro Infant, Department of Pediatrics , School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) , Porto Alegre , Rio Grande do Sul state , Brazil.
Pontifícia Universidade Católica do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although varicella is usually a mild and self-limited disease, complications can occur. In 1998, the World Health Organization recommended varicella vaccination for countries where the disease has a significant public health burden. Nonetheless, concerns about a shift in the disease to older groups, an increase in herpes zoster in the elderly and cost-effectiveness led many countries to postpone universal varicella vaccine introduction. In this review, we summarize the accumulating evidence, available mostly from high and middle-income countries supporting a high impact of universal vaccination in reductions of the incidence of the disease and hospitalizations and its cost-effectiveness. We have also observed the effect of herd immunity and noted that there is no definitive and consistent association between vaccination and the increase in herpes zoster incidence in the elderly.

Indexed as

Global HealthImmunization ProgramsAgedChickenpoxChickenpox VaccineChildCost-Benefit AnalysisHerpesvirus 3, HumanHerpes ZosterHospitalizationHumansIncidenceChickenpox VaccineChickenpoxChickenpox VaccineHerpes ZosterImmunization ProgramsVaricella Zoster Virus

Identifiers

PMID30427766
PMCPMC6605725
OpenAlexW2900512324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.