Evidence map›Paper›PMID 30427487›Full record

Observational studyEinstein (Sao Paulo, Brazil)2018

Indications, clinical outcomes and complications of 1,949 flexible bronchoscopies.

Altair da Silva Costa, Paulo Rogerio Scordamaglio, Iunis Suzuki, Addy Lidvina Mejia Palomino, Marcia Jacomelli

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Einstein (Sao Paulo, Brazil), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Guideline
  2. Review
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  7. Observational
  8. Exploring Insulin Production Following Alveolar Islet Transplantation (AIT).International journal of molecular sciences · 2021
    Article
  9. Can Airway Abnormalities be the Elephant in the Room in Children with Congenital Heart Disease?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Altair da Silva CostaHospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Paulo Rogerio ScordamaglioHospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Iunis SuzukiHospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Addy Lidvina Mejia PalominoHospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Marcia JacomelliHospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Hospital Israelita Albert Einstein · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe indications, clinical outcomes and complications of flexible bronchoscopy.

methodsA descriptive observational study of bronchoscopies performed at the endoscopy service of Hospital Israelita Albert Einstein . Demographic (age, gender and origin) and medical (indications and results of endoscopy and diagnostic tests, such as biopsy collection, lavage, cytology and culture) data were analyzed. Electronic medical records with incomplete data or reporting interventional procedures were excluded.

resultsOver a three-year period (2013 to 2016), a total of 1,949 bronchoscopies were performed by respiratory endoscopy team and anesthesia specialists of the hospital. The mean age of patients was 57.7±21.9 years (range of 3 days to 99 years), with prevalence of males (56.4%). The procedures were mostly (86.3%) elective and 30.7% were carried out in the intensive care unit. Major indications for bronchoscopy were infection or secretion (42.4%), followed by suspected neoplasm (10.8%). Endoscopic changes were reported in 91.9% of cases, with more than one change described in approximately 6.9% of patients. Positive results were obtained via direct testing or culture in 36.3% and 53.9% of 1,399 bronchoalveolar lavages, respectively. The overall diagnostic yield (bronchoalveolar lavage and biopsy) was 72.6%. Mild adverse event rate was 7.2%. The rate of severe adverse events requiring additional intervention was 0.5% (pneumothorax, 0.4%; severe bleeding with patient death, 0.1%).

conclusionLower airway endoscopy is critical for respiratory disease assessment, diagnosis and treatment. Flexible bronchoscopy is associated with good diagnostic yield and minimal inherent risk.

Indexed as

AdolescentAdultAgedAged, 80 and overBronchoalveolar Lavage FluidBronchoscopyChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMiddle AgedProspective StudiesRespiratory Tract Diseases

Identifiers

PMID30427487
PMCPMC6223942
OpenAlexW2901999298

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.