Evidence map›Paper›PMID 30427124›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2019

Antihypertensive therapy prescribing patterns and correlates of blood pressure control among hypertensive patients with chronic kidney disease.

Oyunbileg Magvanjav, Rhonda M Cooper-DeHoff, Caitrin W McDonough, Yan Gong, Mark S Segal, William R Hogan, Julie A Johnson

Abstract readComparative Study
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

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  12. A feared combination: Hypertension and chronic kidney disease.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Oyunbileg MagvanjavDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida.ORCID 0000-0002-2426-9157
Rhonda M Cooper-DeHoffDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida.
Caitrin W McDonoughDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida.
Yan GongDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida.ORCID 0000-0002-8218-1620
Mark S SegalDivision of Nephrology, Hypertension and Renal Transplant, Department of Medicine, University of Florida, and North Florida/South Georgia Veterans Health System, Gainesville, Florida.
William R HoganDepartment of Health Outcomes and Biomedical Informatics, University of Florida College of Medicine, Gainesville, Florida.
Julie A JohnsonDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida.
University of Florida · USUniversity of Florida Health · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
REnal TrAIning & reteNtion (RETAIN) ProgramT32DK104721 · NIDDK · UNIVERSITY OF FLORIDA · PI SEGAL, MARK S., WOOD, CHARLES E · 2015 to 2019
$1.6M
NCATS NIH HHS KL2 TR001429NCATS NIH HHS UL1 TR001427NIDDK NIH HHS T32 DK104721NIH HHS T32 DK104721
6 · The paper itself

Abstract

We used electronic health records (EHRs) data from 5658 ambulatory chronic kidney disease (CKD) patients with hypertension and prescribed antihypertensive therapy to examine antihypertensive drug prescribing patterns, blood pressure (BP) control, and risk factors for resistant hypertension (RHTN) in a real-world setting. Two-thirds of CKD patients and three-fourths of those with proteinuria were prescribed guideline-recommended renoprotective agents including an angiotensin-converting enzyme inhibitor (ACEI) or an angiotensin receptor blocker (ARB); however, one-third were not prescribed an ACEI or ARB. CKD patients, particularly those with stages 1-2 CKD, who were prescribed regimens including beta-blocker (BB) + diuretic or ACEI/ARB + BB + diuretic were more likely to have controlled BP (<140/90 mm Hg) compared to those prescribed other combinations. Risk factors for RHTN included African American race and major comorbidities. Clinicians may use these findings to tailor antihypertensive therapy to the needs of each patient, including providing CKD stage-specific treatment, and better identify CKD patients at risk of RHTN.

Indexed as

Adrenergic beta-AntagonistsAgedAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsBlack or African AmericanBlood PressureCase-Control StudiesComorbidityDiureticsDrug CombinationsFemaleHumansHypertensionHypertension, MalignantMaleAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsDiureticsDrug Combinationsantihypertensive drugsblood pressure controlchronic kidney diseasecombination therapydrug prescribingelectronic health recordshypertension

Identifiers

PMID30427124
PMCPMC6329007
OpenAlexW2901529192

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.