Evidence map›Paper›PMID 30426710›Full record

ArticleObesity (Silver Spring, Md.)2018

Melanocortin-3 Receptors Expressed on Agouti-Related Peptide Neurons Inhibit Feeding Behavior in Female Mice.

Clemence Girardet, Daniel L Marks, Andrew A Butler

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Clemence GirardetDepartment of Pharmacology & Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Daniel L MarksDepartment of Pediatrics, Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, Oregon, USA.
Andrew A ButlerDepartment of Pharmacology & Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-7196-0170
Scripps Research Institute · USOregon Health & Science University · US

Funding

Melanocortin-3 Receptor Regulation of Physical Activity and MetabolismR01DK073189 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI BUTLER, ANDREW ALISTAIR · 2007 to 2015
$3.4M
Hypothalamic Mechanisms in CachexiaR01DK070333 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI MARKS, DANIEL L. · 2004 to 2013
$2.6M
(PQD6) Hypothalamic Inflammation in the Initiation of CachexiaR01CA184324 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MARKS, DANIEL L. · 2014 to 2017
$1.8M
NCI NIH HHS CA184324NCI NIH HHS R01 CA184324NIDDK NIH HHS DK073189NIDDK NIH HHS R01 DK070333NIDDK NIH HHS R01 DK073189NIH HHS DK073189
6 · The paper itself

Abstract

objectiveActivation of hypothalamic agouti-related peptide expressing (AgRP)

methodsAgRP-MC3R mice expressing MC3Rs selectively in AgRP

resultsIn females, food intake of AgRP-IRES-Cre

conclusionsMC3Rs expressed on AgRP

Indexed as

Agouti-Related ProteinAnimalsDisease Models, AnimalFeeding BehaviorFemaleMiceMice, TransgenicNeuronsReceptor, Melanocortin, Type 3Agouti-Related ProteinReceptor, Melanocortin, Type 3

Identifiers

PMID30426710
PMCPMC7294842
OpenAlexW2901687573

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.