ArticleNeurogastroenterology and motility2019
High-resolution impedance manometry parameters in the evaluation of esophageal function of non-obstructive dysphagia patients.
Article in Neurogastroenterology and motility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Esophageal Hypervigilance and Visceral Anxiety Are Contributors to Symptom Severity Among Patients Evaluated With High-Resolution Esophageal Manometry.The American journal of gastroenterology · 2020Trial
- Investigating the utility of EndoFLIP™ as a screening tool for pathologic reflux EndoFLIP™ as a screening tool for GERD.Surgical endoscopy · 2026Article
- Long-term Prognosis and Prognostic Factors in Ineffective Esophageal Motility.Journal of neurogastroenterology and motility · 2025Article
- Impedance planimetry and panometry (EndoFLIP™) can replace manometry in preoperative anti-reflux surgery assessment.Surgical endoscopy · 2024Article
- Endoscopic impedance planimetry versus high-resolution manometry (HRM) for pre-operative motility evaluation in anti-reflux surgery.Surgical endoscopy · 2024Article
- The Clinical Usefulness of Functional Luminal Imaging Probe in Esophageal Dysmotility Disorder.Journal of neurogastroenterology and motility · 2022Article
- A Comparative Assessment of the Diagnosis of Swallowing Impairment and Gastroesophageal Reflux in Canines and Humans.Frontiers in veterinary science · 2022Review
- Combination of Symptom Profile, Endoscopic Findings, and Esophageal Mucosal Histopathology Helps to Differentiate Achalasia from Refractory Gastroesophageal Reflux Disease.Diagnostics (Basel, Switzerland) · 2021Article
- Normal Values of High-resolution Manometry Parameters With Provocative Maneuvers.Journal of neurogastroenterology and motility · 2021Article
- Variations in Clinical Practice of Esophageal High-resolution Manometry: A Nationwide Survey.Journal of neurogastroenterology and motility · 2021Article
- Chicago classification version 4.0Neurogastroenterology and motility · 2021Review
- Multiple rapid swallows and rapid drink challenge in patients with esophagogastric junction outflow obstruction on high-resolution manometry.Neurogastroenterology and motility · 2021Article
- [Diagnosis of Dysphagia: High Resolution Manometry & EndoFLIP].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Review
- Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0Neurogastroenterology and motility · 2021Review
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Authors and funding
8 authors.
Funding
Abstract
backgroundHigh-resolution impedance manometry (HRIM) allows evaluation of esophageal bolus retention, flow, and pressurization. We explored novel HRIM measures and assessed their temporal relationship to dysphagia symptoms for boluses of different volume and consistency in non-obstructive dysphagia (NOD) patients.
methodsThirty-three NOD patients (n = 19 minor or no disorder of peristalsis ("Normal") and n = 14 esophagogastric junction outflow obstruction ("EGJOO")) were evaluated with HRIM. Patients were administered 5 and 10 mL liquid, semisolid, and 2 and 4 cm solid boluses and indicated bolus perception during individual swallows using a 5-point Likert scale. HRIM was analyzed to assess Chicago Classification and pressure flow metrics, esophageal impedance integral (EII) ratio, and bolus flow time (BFT). KEY
resultsOverall, bolus perception increased with increasing bolus consistency (P < 0.001), but did not differ significantly between EGJOO and Normal patients. EGJOO patients had higher IRP4, higher levels of bolus residual (ie, EII ratio and IR), and restricted esophageal emptying. The results for linking semisolid bolus perception to semisolid-derived measures revealed more biomechanically plausible and consistent patterns when compared to those derived for liquid boluses. In Normal patients, perception of boluses of heavier viscosity was related to higher bolus flow resistance during transport, whilst in EGJOO, perception was related to restriction of esophageal emptying. CONCLUSION & INFERENCES: These novel pressure-impedance measures may aid in the evaluation of NOD patients by revealing abnormal motor patterns, which may explain symptom generation. Future studies are needed to evaluate which of these measures are worthy of calculation and to establish protocol settings that allow for their meaningful interpretation.
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