Evidence map›Paper›PMID 30426462›Full record

ReviewPharmacoEconomics2019

Autologous Chondrocyte Implantation with Chondrosphere for Treating Articular Cartilage Defects in the Knee: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

Xavier Armoiry, Ewen Cummins, Martin Connock, Andrew Metcalfe, Pamela Royle, Rhona Johnston, Jeremy Rodrigues, Norman Waugh, Hema Mistry

Abstract readReview
PubMed Publisher
In one paragraph

Review in PharmacoEconomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Clinical evaluation of a resurfacing device implant for femoral osteochondral defects greater than 1 cmEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. From Cells to Organs: The Present and Future of Regenerative Medicine.Advances in experimental medicine and biology · 2022
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xavier ArmoiryWarwick Evidence, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Ewen CumminsMcMDC, Harrogate, UK.
Martin ConnockWarwick Evidence, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Andrew MetcalfeWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.
Pamela RoyleWarwick Evidence, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Rhona JohnstonMcMDC, Harrogate, UK.
Jeremy RodriguesNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, OX3 7HE, UK.
Norman WaughWarwick Evidence, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Hema MistryWarwick Evidence, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK. Hema.Mistry@warwick.ac.uk.ORCID 0000-0002-5023-1160
University of Warwick · GBHarrogate District Hospital · GBNuffield Orthopaedic Centre · GB

Funding

Department of Health 15/69/10Department of Health PDF-2017-10-075
6 · The paper itself

Abstract

Chondrosphere (Spherox) is a form of autologous chondrocyte implantation (ACI). It is licensed for repair of symptomatic articular cartilage defects of the femoral condyle and the patella of the knee with defect sizes up to 10 cm

Indexed as

AdultCartilage, ArticularChondrocytesCost-Benefit AnalysisHumansKnee JointQuality-Adjusted Life YearsRandomized Controlled Trials as TopicTechnology Assessment, BiomedicalTransplantation, Autologous

Identifiers

PMID30426462
OpenAlexW2901371325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.