Evidence map›Paper›PMID 30426450›Full record

ReviewApplied health economics and health policy2019

Peristeen Transanal Irrigation System to Manage Bowel Dysfunction: A NICE Medical Technology Guidance.

Megan Dale, Helen Morgan, Kimberly Carter, Judith White, Grace Carolan-Rees

Open access · hybridAbstract readReview
In one paragraph

Review in Applied health economics and health policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. 'Everyone has their own way-there's no protocol'. An Australian qualitative study of clinician perspectives on the management of low anterior resection syndrome.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
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  5. Review
  6. Observational
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  9. Review
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  13. [Treatment of Fecal Incontinence: A Surgical Approach].Acta gastroenterologica Latinoamericana
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Megan DaleCedar, Cardiff and Vale University Health Board, Cardiff, UK. Megan.Dale@wales.nhs.uk.ORCID 0000-0001-7229-5109
Helen MorganCedar, Cardiff University, Cardiff, UK.
Kimberly CarterNational Institute for Health and Care Excellence, Manchester, UK.
Judith WhiteCedar, Cardiff and Vale University Health Board, Cardiff, UK.
Grace Carolan-ReesCedar, Cardiff and Vale University Health Board, Cardiff, UK.
Cardiff and Vale University Health Board · GBCardiff University · GBNational Institute for Health and Care Excellence · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Peristeen transanal irrigation system is intended to allow people with bowel dysfunction to flush out the lower part of the bowel as part of their bowel management strategy. Peristeen was the subject of an evaluation by the National Institute for Health and Care Excellence, through its Medical Technologies Evaluation Programme, for the management of bowel dysfunction. The company, Coloplast, submitted a case for adoption of the technology, claiming that the technology improves the severity of chronic constipation or faecal incontinence and improves quality of life for people with bowel dysfunction. Other claimed benefits included reduced frequency of UTIs, stoma surgery and hospitalisation rates, as well as reduced costs. The submission was critiqued by Cedar. The clinical evidence assessed included one randomised controlled trial, and 12 observational studies for adults and 11 studies for children. Although there are limitations in the evidence, the assessed studies show some improvement in outcomes for patients who choose to continue using Peristeen. The committee heard from patient experts that Peristeen had improved their lives and allowed them increased independence. The submitted economic evidence had numerous flaws, however following Cedar's changes to the model, and additional sensitivity analysis, the use of Peristeen was judged unlikely to be cost incurring compared with standard bowel care. The Peristeen transanal irrigation system received a positive recommendation in Medical Technologies Guidance 36.

Indexed as

Gastric LavageTransanal Endoscopic SurgeryAdvisory CommitteesConstipationCost-Benefit AnalysisEnglandFecal IncontinenceFemaleHumansMaleMiddle AgedQuality of Life

Identifiers

PMID30426450
PMCPMC6345726
OpenAlexW2900591360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.