SynthesisNeurocritical care2019
Assessment and Comparison of the Four Most Extensively Validated Prognostic Scales for Intracerebral Hemorrhage: Systematic Review with Meta-analysis.
Synthesis in Neurocritical care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage.Neurocritical care · 2024Guideline
- Extension of the FUNC Score for Prediction of 12-Month Functional Independence after Primary Intracerebral Hemorrhage.Neurocritical care · 2026Article
- Early care limitation after ICH in a population-based study: what drives clinicians' decisions?European stroke journal · 2026Article
- Prognostic Significance of Triglyceride Glucose Index in Intracerebral Hemorrhage.Medical sciences (Basel, Switzerland) · 2026Article
- Deep Learning for Dynamic Prognostic Prediction in Minimally Invasive Surgery for Intracerebral Hemorrhage: Model Development and Validation Study.JMIR medical informatics · 2026Article
- Prognostic Accuracy of Common Mortality Prognostic Scales in Very Old Patients with Intracerebral Haemorrhage.Annals of neurosciences · 2025Article
- Predicting 90-day postoperative outcomes in spontaneous supratentorial intracerebral hemorrhage: a double-center study of clinical-radiomics integration using non-contrast CT.Frontiers in neurology · 2025Article
- Prognostic value of temporalis muscle thickness as a marker of sarcopenia in intracerebral hemorrhage.Frontiers in neurology · 2025Article
- A machine learning model based on results of a comprehensive radiological evaluation can predict the prognosis of basal ganglia cerebral hemorrhage treated with neuroendoscopy.Frontiers in neurology · 2024Article
- The National Institutes of Health Stroke Scale is comparable to the ICH score in predicting outcomes in spontaneous acute intracerebral hemorrhage.Frontiers in neurology · 2024Article
- Whole-brain diffusion tensor imaging predicts 6-month functional outcome in acute intracerebral haemorrhage.Journal of neurology · 2023Article
- ANAID-ICH nomogram for predicting unfavorable outcome after intracerebral hemorrhage.CNS neuroscience & therapeutics · 2022Article
- Acute corticospinal tract diffusion tensor imaging predicts 6-month functional outcome after intracerebral haemorrhage.Journal of neurology · 2022Article
- Hyperacute prediction of functional outcome in spontaneous intracerebral haemorrhage: systematic review and meta-analysis.European stroke journal · 2022Review
- Validation of the ICH score and ICH-GS in a Peruvian surgical cohort: a retrospective study.Neurosurgical review · 2022Article
- Validation of the newly conceived Surgical Swedish ICH grading scale for surgically treated patients with intracerebral hemorrhage: patient series.Journal of neurosurgery. Case lessons · 2021Article
- Postsurgical functional outcome prediction model using deep learning framework (Prediction One, Sony Network Communications Inc.) for hypertensive intracerebral hemorrhage.Surgical neurology international · 2021Article
- Enhancing Robustness of Machine Learning Integration With Routine Laboratory Blood Tests to Predict Inpatient Mortality After Intracerebral Hemorrhage.Frontiers in neurology · 2021Article
- IL-33 as a Novel Serum Prognostic Marker of Intracerebral Hemorrhage.Oxidative medicine and cellular longevity · 2021Article
- Treatment of intracerebral hemorrhage: From specific interventions to bundles of care.International journal of stroke : official journal of the International Stroke Society · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectiveIntracerebral hemorrhage (ICH) is a devastating disorder, responsible for 10% of all strokes. Several prognostic scores have been developed for this population to predict mortality and functional outcome. The aim of this study was to determine the four most frequently validated and most widely used scores, assess their discrimination for both outcomes by means of a systematic review with meta-analysis, and compare them using meta-regression.
methodsPubMed, ISI Web of Knowledge, Scopus, and CENTRAL were searched for studies validating the ICH score, ICH-GS, modified ICH, and the FUNC score in ICH patients. C-statistic was chosen as the measure of discrimination. For each score and outcome, C-statistics were aggregated at four different time points using random effect models, and heterogeneity was evaluated using the I
resultsFifty-three studies were found validating the original ICH score, 14 studies were found validating the ICH-GS, eight studies were found validating the FUNC score, and five studies were found validating the modified ICH score. Most studies attempted outcome prediction at 3 months or earlier. Pooled C-statistics ranged from 0.76 for FUNC functional outcome prediction at discharge to 0.85 for ICH-GS mortality prediction at 3 months, but heterogeneity was high across studies. RVE showed the ICH score retained the highest discrimination for mortality (c = 0.84), whereas the modified ICH score retained the highest discrimination for functional outcome (c = 0.80), but these differences were not statistically significant.
conclusionsThe ICH score is the most extensively validated score in ICH patients and, in the absence of superior prediction by other scores, should preferably be used. Further studies are needed to validate prognostic scores at longer follow-ups and assess the reasons for heterogeneity in discrimination.
Indexed as
Identifiers
30426449What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.