Evidence map›Paper›PMID 30426391›Full record

ArticleThe European physical journal. E, Soft matter2018

Polynucleotide transport through lipid membrane in the presence of starburst cyclodextrin-based poly(ethylene glycol)s.

Zahra Eskandani, Tony Le Gall, Tristan Montier, Pierre Lehn, Fabien Montel, Loïc Auvray, Cécile Huin, Philippe Guégan

Abstract read
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In one paragraph

Article in The European physical journal. E, Soft matter, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zahra EskandaniLAMBE, Univ Evry, CNRS, CEA, Université Paris-Saclay, 91025, Evry, France.
Tony Le GallINSERM UMR 1078, Faculté de Médecine, Université de Bretagne Occidentale, Université Européenne de Bretagne, 22 avenue Camille Desmoulins, 29238, Brest Cedex 3, France.
Tristan MontierINSERM UMR 1078, Faculté de Médecine, Université de Bretagne Occidentale, Université Européenne de Bretagne, 22 avenue Camille Desmoulins, 29238, Brest Cedex 3, France.
Pierre LehnINSERM UMR 1078, Faculté de Médecine, Université de Bretagne Occidentale, Université Européenne de Bretagne, 22 avenue Camille Desmoulins, 29238, Brest Cedex 3, France.
Fabien MontelMatière et Systèmes Complexes, CNRS-UMR 7057, Université Paris-Diderot, 10 rue Alice Domon et Léonie Duquet, 75205, Paris cedex 13, France.
Loïc AuvrayMatière et Systèmes Complexes, CNRS-UMR 7057, Université Paris-Diderot, 10 rue Alice Domon et Léonie Duquet, 75205, Paris cedex 13, France.
Cécile HuinLAMBE, Univ Evry, CNRS, CEA, Université Paris-Saclay, 91025, Evry, France.
Philippe GuéganSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, Equipe Chimie des Polymères, 4 place Jussieu, F-75005, Paris, France. philippe.guegan@sorbonne-universite.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Symmetrical cyclodextrin-based 14-arm star polymers with poly(ethylene glycol) PEG branches were synthesized and characterized. Interactions of the star polymers with lipid bilayers were studied by the "black lipid membrane" technique in order to demonstrate the formation of monomolecular artificial channels. The conditions for the insertion are mainly based on dimensions and amphiphilic properties of the star polymers, in particular the molar mass of the water-soluble polymer branches. Translocation of single-strand DNA (ssDNA) through those synthetic nanopores was investigated, and the close dimension between the cross-section of ssDNA and the cyclodextrin cavity led to an energy barrier that slowed down the translocation process.

Indexed as

Base SequenceBiological TransportCell MembraneCyclodextrinsDNALipid BilayersPolyethylene GlycolsPolynucleotidesCyclodextrinsDNALipid BilayersPolyethylene GlycolsPolynucleotidesPolymers: From Adsorption to Translocation - Topical Issue in Memoriam Loïc Auvray (1956-2016)

Identifiers

PMID30426391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.