Evidence map›Paper›PMID 30426181›Full record

ArticlePsychopharmacology2018

Effects of intra-accumbal or intra-prefrontal cortex microinjections of adenosine 2A receptor ligands on responses to cocaine reward and seeking in rats.

K Wydra, A Suder, M Frankowska, D O Borroto Escuela, K Fuxe, M Filip

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06739304 (The Effectiveness of Mindfulness-based Relapse Prevention), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06739304 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effectiveness of Mindfulness-based Relapse Prevention: A Randomized Controlled Trial Study

TypeinterventionalSponsorSir Run Run Shaw HospitalRan2023 to 2023Enrolled1,200ConditionsSubstance Use DisorderArmsMindfulness-based Relapse Prevention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Adenosine APsychopharmacology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Allosteric Interactions between Adenosine AInternational journal of molecular sciences · 2021
    Review
  7. Article
  8. Adenosine ACells · 2020
    Review
  9. Adenosine AFrontiers in molecular neuroscience · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

K WydraDepartment of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, 12 Smetna Street, PL-31-343, Kraków, Poland. wydra@if-pan.krakow.pl.
A SuderDepartment of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, 12 Smetna Street, PL-31-343, Kraków, Poland.
M FrankowskaDepartment of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, 12 Smetna Street, PL-31-343, Kraków, Poland.
D O Borroto EscuelaDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
K FuxeDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
M FilipDepartment of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, 12 Smetna Street, PL-31-343, Kraków, Poland.
Maj Institute of Pharmacology · PLKarolinska Institutet · SE

Funding

Instytut Farmakologii, Polskiej Akademii Nauk statutory fundsNarodowe Centrum Nauki 2011/03/N/NZ7/06294Swedish Medical Research Council 04X-715
6 · The paper itself

Abstract

RATIONALE AND

objectivesMany studies indicated that adenosine via its A

methodsThe effects of local bilateral microinjections of the selective A

resultsThe intra-NAc shell, but not intra-infralimbic PFc, administration of CGS 21680 significantly reduced the number of active lever presses and the number of cocaine (0.25 mg/kg) infusions. However, tonic activation of A

conclusionThe results strongly support the involvement of accumbal shell A

Indexed as

Adenosine A2 Receptor AgonistsAnimalsCocaineCocaine-Related DisordersConditioning, OperantDopamine Uptake InhibitorsDrug-Seeking BehaviorLigandsMaleMicroinjectionsNucleus AccumbensPrefrontal CortexRatsRats, WistarReceptor, Adenosine A2ARewardAdenosine A2 Receptor AgonistsCocaineDopamine Uptake InhibitorsLigandsReceptor, Adenosine A2AAdenosine A2A receptor ligandsCocaine seekingCocaine self-administrationLocal microinjectionNucleus accumbensPrefrontal cortexRats

Identifiers

PMID30426181
PMCPMC6267142
OpenAlexW2901418979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.