Evidence map›Paper›PMID 30426028›Full record

ArticleMolecular biology research communications2018

Computational prediction of miRNAs in Nipah virus genome reveals possible interaction with human genes involved in encephalitis.

Sandeep Saini, Chander Jyoti Thakur, Varinder Kumar, Suchita Tandon, Varuni Bhardwaj, Sonia Maggar, Stanzin Namgyal, Gurpreet Kaur

Open access · greenAbstract read
In one paragraph

Article in Molecular biology research communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Hepatitis B Virus and microRNAs: A Bioinformatics Approach.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandeep SainiDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.
Chander Jyoti ThakurDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.
Varinder KumarDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.
Suchita TandonDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.
Varuni BhardwajDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.
Sonia MaggarDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.
Stanzin NamgyalDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.
Gurpreet KaurDepartment of Bioinformatics, G.G.D.S.D. College, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current re-emergence of Nipah virus (NiV) in India caused 11 deaths so far and many patients were kept in quarantine. A thorough study of previous outbreaks occurred in Malaysia, Bangladesh and India represents cases with high rate of fatality due to acute encephalitis. Our work involves genome analysis of NiV for prediction of miRNAs and their targeted genes in human in order to understand encephalitis origin. Ab-intio program-VMir was used for initial screening of genome, obtained nine pre-miRNAs was analyzed by ViralMir to check for any pseudo pre-miRNAs. Eighteen functional mature miRNAs were extracted from pre-miRNAs by using Mature-Bayes tool, which targets 669 genes in human genome as retrieved by miRDB. Gene ontology terms by PANTHER provide important pathways in which target genes were involved like Axon guidance, T cell activation, and nicotinic acetylcholine receptor signaling. Significant outcome was obtained after NCBI Gene and OMIM database mining and literature search for predicted target genes.

Indexed as

EncephalitismiRNANipahTarget genes

Identifiers

PMID30426028
PMCPMC6203886
OpenAlexW2884128574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.