Evidence map›Paper›PMID 30426017›Full record

SynthesisBioMed research international2018

Prognostic Value of Frailty for Older Patients with Heart Failure: A Systematic Review and Meta-Analysis of Prospective Studies.

Xige Wang, Changli Zhou, Yuewei Li, Huimin Li, Qinqin Cao, Feng Li

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. The role of frailty in advanced HF and cardiac transplantation.Frontiers in cardiovascular medicine · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xige WangSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, Jilin 130020, China.ORCID 0000-0002-7860-116X
Changli ZhouSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, Jilin 130020, China.
Yuewei LiSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, Jilin 130020, China.
Huimin LiSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, Jilin 130020, China.ORCID 0000-0001-9072-646X
Qinqin CaoSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, Jilin 130020, China.ORCID 0000-0002-1698-3545
Feng LiSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, Jilin 130020, China.ORCID 0000-0001-7423-8730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNumerous studies have investigated the prognostic role of frailty in elderly patients with heart failure (HF), but the limited size of the reported studies has resulted in continued uncertainty regarding its prognostic impact. The aim of this study was to integrate the findings of all available studies and estimate the impact of frailty on the prognosis of HF by performing a systematic review and meta-analysis.

methodsPubMed, Embase, Cochrane, and Web of Science databases were searched from inception to November 8

resultsA total of 10 studies involving 3033 elderly patients with HF were included in the systematic review and meta-analysis. All eligible studies indicated that frailty was of prognostic significance for HF patients. The HRs for the effects of frailty on all-cause mortality were 1.70 (95% confidence interval (CI): 1.41-2.04), based on the pooling of six studies that provided related data. However, publication bias was observed among the studies.

conclusionsFrailty has a high prevalence among older patients with HF. Elderly HF patients with frailty have a poorer prognosis than those without frailty. Further studies are now required to implement the use of frailty assessment tools and explore effective interventions for frailty in older HF patients.

Indexed as

Frail ElderlyHeart FailureModels, CardiovascularAgedAged, 80 and overFemaleHumansMalePrevalencePrognosis

Identifiers

PMID30426017
PMCPMC6217893

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.