Evidence map›Paper›PMID 30425904›Full record

ArticleBalkan journal of medical genetics : BJMG2018

Family History as an Important Factor for Stratifying Participants in Genetic Studies of Major Depression.

B Zalar, A Blatnik, A Maver, Z Klemenc-Ketiš, B Peterlin

Abstract read
In one paragraph

Article in Balkan journal of medical genetics : BJMG, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

B ZalarUniversity Psychiatric Hospital Ljubljana, Clinical Institute of Medical Genetics, University Medical Center Ljubljana, Ljubljana Slovenia.
A BlatnikDepartment of Family Medicine, Maribor Medical School, Maribor, Slovenia.
A MaverDepartment of Family Medicine, Maribor Medical School, Maribor, Slovenia.
Z Klemenc-KetišDepartment of Family Medicine, Ljubljana Medical School, Ljubljana, Slovenia.
B PeterlinDepartment of Family Medicine, Maribor Medical School, Maribor, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is estimated to affect 350 million people worldwide. The World Mental Health Survey conducted in 17 countries found that, on average, about one in 20 people reported having an episode of depression in the previous year. Although depression has been shown to be moderately heritable by studies conducted in the past, the search for its so-called missing heritability has so far been unsuccessful. The difficulty in identifying common genetic variants predisposing to depression could be due to large sample sizes needed to detect small effects on genetic risk and the heterogeneous nature of major depressive disorder (MDD). The aim of our study was to determine whether there was a connection between a family history of depression in MDD patients and the presence of putative risk variants in the well-studied

Indexed as

COMT geneFamily historyMajor depressive disorder (MDD)PCLO geneSLC6A4 gene

Identifiers

PMID30425904
PMCPMC6231308

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.