Evidence map›Paper›PMID 30425884›Full record

ArticlePeerJ2018

Application of a MALDI-TOF analysis platform (ClinProTools) for rapid and preliminary report of MRSA sequence types in Taiwan.

Hsin-Yao Wang, Frank Lien, Tsui-Ping Liu, Chun-Hsien Chen, Chao-Jung Chen, Jang-Jih Lu

Abstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Accurately IdentifyingDiagnostics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. ExploringJournal of mass spectrometry and advances in the clinical lab · 2023
    Article
  10. Article
  11. Review
  12. Rapid Identification ofFrontiers in microbiology · 2022
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Rapid Classification of Multilocus Sequence Subtype for Group BFrontiers in cellular and infection microbiology · 2020
    Article
  18. Community-Acquired Methicillin-ResistantInfection and drug resistance · 2020
    Article
  19. Article
  20. Rapid Discrimination of Methicillin-ResistantPathogens (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hsin-Yao Wang *Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Tauyuan, Taiwan.ORCID 0000-0001-5581-6793
Frank Lien *Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Tauyuan, Taiwan.
Tsui-Ping LiuDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Tauyuan, Taiwan.
Chun-Hsien ChenDepartment of Information Management, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0001-8353-0215
Chao-Jung ChenGraduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan.
Jang-Jih LuDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Tauyuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe accurate and rapid preliminarily identification of the types of methicillin-resistant

methodsThe mass spectra of 306 MRSA isolates were obtained from multiple reference hospitals in Taiwan. The multilocus sequence types (MLST) of the isolates were determined. The spectra were analyzed for the selection of characteristic peaks by using the ClinProTools software. Furthermore, various machine learning (ML) algorithms were used to generate binary and multiclass models for classifying the major MLST types (ST5, ST59, and ST239) of MRSA.

resultsA total of 10 peaks with the highest discriminatory power (

conclusionsA combination of MALDI-TOF MS analysis and ML models is a potentially accurate, objective, and efficient tool for infection control and outbreak investigation.

Indexed as

ClinProToolsLineage typingMALDI-TOFMLMLSTMRSA

Identifiers

PMID30425884
PMCPMC6228551

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.