ArticleDisease markers2018
Serum Uric Acid as an Independent Risk Factor for the Presence and Severity of Early-Onset Coronary Artery Disease: A Case-Control Study.
Article in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Serum uric acid-to-creatinine ratio as a predictor for the severity of coronary artery lesions.BMC research notes · 2026Article
- IL-6 and lL-17 as potential biomarkers for premature coronary artery disease: a cross-sectional study.BMC cardiovascular disorders · 2026Article
- Current status of premature myocardial infarction research in China: a systematic review and international comparative perspective.Frontiers in cardiovascular medicine · 2026Review
- The impact of uric acid on acute coronary syndrome prognosis in elderly patients.Annals of medicine · 2025Article
- New Insights into Uric Acid Metabolism in the Pathophysiology of Ischaemic Heart Disease.European cardiology · 2025Review
- Cell-free plasma telomere length correlated with the risk of cardiovascular events using machine learning classifiers.Scientific reports · 2024Article
- Hyperuricemia as a Risk Factor in Hypertension among Patients with Very High Cardiovascular Risk.Healthcare (Basel, Switzerland) · 2023Article
- Correlation Analysis and Diagnostic Value of Serum Homocysteine, Cystatin C and Uric Acid Levels with the Severity of Coronary Artery Stenosis in Patients with Coronary Heart Disease.International journal of general medicine · 2023Article
- Association between serum gamma-glutamyltransferase and early-onset coronary artery disease: a retrospective case-control study.Annals of medicine · 2023Article
- Serum Uric Acid Levels in Relation to Atrial Fibrillation: A Case-Control Study.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- The Role of Uric Acid in Acute and Chronic Coronary Syndromes.Journal of clinical medicine · 2021Review
- Higher uric acid is associated with better discharge recovery and short-term outcome in stroke patients treated with thrombolysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Hyperuricemia Predicts Adverse Outcomes After Myocardial Infarction With Non-obstructive Coronary Arteries.Frontiers in medicine · 2021Article
- Serum fatty acids profile and association with early-onset coronary artery disease.Therapeutic advances in chronic disease · 2021Article
- Association between ALMS 1 variants and early-onset coronary artery disease: a case-control study in Chinese population.Bioscience reports · 2020Article
- Observational
- Association Between Serum Uric Acid Levels and Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis of Observational Studies.Frontiers in neurology · 2019Article
- Serum adenosine deaminase activity and coronary artery disease: a retrospective case-control study based on 9929 participants.Therapeutic advances in chronic disease · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serum uric acid (UA) is the final product of purine metabolism in humans. The present study is aimed at identifying the potential association between serum UA and early-onset coronary artery disease (EOCAD). The study population consisted of 1093 EOCAD patients aged ≤50 years, and 1117 age- and sex-matched apparently healthy people served as controls. The concentrations of UA were measured by uricase method. The severity of CAD was evaluated by Gensini score. The mean serum level of UA was 5.843 ± 1.479 mg/dl in EOCAD patients and 5.433 ± 1.529 mg/dl in controls. Serum UA levels were significantly higher in the EOCAD group than those in the control group (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.