Evidence map›Paper›PMID 30425691›Full record

ArticleFrontiers in microbiology2018

Topical Application of a Vitamin A Derivative and Its Combination With Non-ablative Fractional Laser Potentiates Cutaneous Influenza Vaccination.

Peiyu Li, Ji Wang, Miao Cao, Qiwen Deng, Shibo Jiang, Mei X Wu, Lu Lu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. The Life ofMicroorganisms · 2023
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Laser adjuvant for vaccination.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Peiyu LiKey Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Ji WangWellman Center for Photomedicine, Massachusetts General Hospital, Department of Dermatology, Harvard Medical School, Boston, MA, United States.
Miao CaoKey Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Qiwen DengDepartment of Infectious Diseases and the Key Lab of Endogenous Infection, Shenzhen Nanshan People's Hospital, Guangdong Medical University, Shenzhen, China.
Shibo JiangKey Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Mei X WuWellman Center for Photomedicine, Massachusetts General Hospital, Department of Dermatology, Harvard Medical School, Boston, MA, United States.
Lu LuKey Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Harvard University · USShanghai Public Health Clinical Center · CNGuangdong Medical College · CNNew York Blood Center · USSun Yat-sen University · CN

Funding

Boosting Flu Vaccination without Adjuvant InjectionR01AI089779 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WU, MEI X · 2011 to 2015
$2.8M
Assessing Social Justice in Economic Evaluation to Scale up Novel MDR-TB RegimensR01AI114458 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DOWDY, DAVID WESLEY · 2015 to 2018
$1.6M
Delivery of Peanut Allergen Powder into Epidermis for Safe ImmunotherapyR21AI135233 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WU, MEI X · 2018 to 2019
$454k
Assessing Social Value in Economic Evaluation to Scale Up Novel TB Drug RegimensR56AI114458 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MERRITT, MARIA WESTON · 2014 to 2014
$302k
NIAID NIH HHS R01 AI089779NIAID NIH HHS R01 AI114458NIAID NIH HHS R21 AI135233NIAID NIH HHS R56 AI114458
6 · The paper itself

Abstract

Skin contains a large number of antigen presenting cells, making intradermal (ID) injection one of the most effective ways for vaccine administration. However, although current adjuvants may cause severe local reactions and inflammations in the skin, no adjuvant has been approved for ID vaccination so far. Here, we report that topical application of all-

Indexed as

all-trans retinoic acidcutaneous adjuvantinfluenza vaccineinterferon regulatory factor 3interferon regulatory factor 7non-ablative fractional lasertype I interferon

Identifiers

PMID30425691
PMCPMC6218415
OpenAlexW2897833709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.