Evidence map›Paper›PMID 30425573›Full record

ArticleCancer management and research2018

Preoperative C-reactive protein/albumin ratio is a significant predictor of survival in bladder cancer patients after radical cystectomy: a retrospective study.

Yadong Guo, Keke Cai, Shiyu Mao, Junfeng Zhang, Longsheng Wang, Ziwei Zhang, Mengnan Liu, Wentao Zhang, Yuan Wu, Yang Yan and 1 more

Abstract read
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yadong GuoDepartment of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, People's Republic of China, 13564368328@163.com, yaoxudong1967@163.com.
Keke CaiDepartment of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Shiyu MaoDepartment of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, People's Republic of China, 13564368328@163.com, yaoxudong1967@163.com.
Junfeng ZhangDepartment of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, People's Republic of China, 13564368328@163.com, yaoxudong1967@163.com.
Longsheng WangDepartment of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, People's Republic of China, 13564368328@163.com, yaoxudong1967@163.com.
Ziwei ZhangDepartment of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, People's Republic of China, 13564368328@163.com, yaoxudong1967@163.com.
Mengnan LiuDepartment of Anhui Medical University, Hefei, People's Republic of China.
Wentao ZhangDepartment of Anhui Medical University, Hefei, People's Republic of China.
Yuan WuDepartment of Anhui Medical University, Hefei, People's Republic of China.
Yang YanDepartment of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, People's Republic of China, 13564368328@163.com, yaoxudong1967@163.com.
Xudong YaoDepartment of Urology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, People's Republic of China, 13564368328@163.com, yaoxudong1967@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarlier studies have indicated the prognostic value of the pretreatment C-reactive protein (CRP)/albumin ratio (CAR) in multiple tumor types. The present study attempts to investigate the predictive role of preoperative CAR in patients with bladder cancer after radical cystectomy (RC), and explores its prognostic index value. PATIENTS AND

methodsA total of 131 patients with bladder cancer after RC between 2009 and 2015 were analyzed in the present study. Overall survival (OS) and progression-free survival (PFS) were estimated using the Kaplan-Meier method and Cox regression analyses. Prediction accuracy was evaluated through the area under the receiver operating characteristic curve (AUC).

resultsThe median follow-up time for all patients in the present retrospective study was 39.72 months (15.51-53.26 months). The Kaplan-Meier curve analysis indicated that bladder cancer patients with high preoperative CAR (>0.2) were significantly associated with decreased PFS and OS (all,

conclusionThe present study demonstrated that CAR can be used as a new prognostic indicator of OS and PFS in patients with bladder cancer after RC. Combining the CAR score with pathological T staging as the CART score appears to be a more effective prognostic indicator of poor OS, but not PFS.

Indexed as

bladder cancerC-reactive protein/albumin ratio (CAR)prognostic modelradical cystectomy

Identifiers

PMID30425573
PMCPMC6205524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.