Evidence map›Paper›PMID 30425480›Full record

ArticleInternational journal of nanomedicine2018

Artificially controlled degradable nanoparticles for contrast switch MRI and programmed cancer therapy.

Tianyang Yun, Yuxin Liu, Shaoqiong Yi, Qi Jia, Yang Liu, Jing Zhou

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Clearable Nanoparticles for Cancer Photothermal Therapy.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tianyang YunDepartment of Thoracic Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, People's Republic of China, sunny301x@sina.com.
Yuxin LiuDepartment of Chemistry, Capital Normal University, Beijing 100048, People's Republic of China, jingzhou@cnu.edu.cn.
Shaoqiong YiDepartment of Thoracic Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, People's Republic of China, sunny301x@sina.com.
Qi JiaDepartment of Chemistry, Capital Normal University, Beijing 100048, People's Republic of China, jingzhou@cnu.edu.cn.
Yang LiuDepartment of Thoracic Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, People's Republic of China, sunny301x@sina.com.
Jing ZhouDepartment of Chemistry, Capital Normal University, Beijing 100048, People's Republic of China, jingzhou@cnu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUtilizing the permeability enhancement and irreversible biomolecule denaturation caused by hyperthermia, photothermal-chemo synergistic therapy has shown great potential in clinical cancer treatment. PURPOSE: The objective of this study was to provide a novel controlled drug release method to improve the efficiency of photothermal-chemo synergistic therapy. PATIENTS AND

methodsHCT116 tumor-bearing mice were selected as modal for the study of cancer theranostics efficiency. The T2 to T1 magnetic resonance imaging contrast switch was studied in vivo. Analyses of the tumor growth of mice were carried out to evaluate the tumor therapy efficiency.

resultsWe developed novel artificially controlled degradable Co

conclusionOur results illustrated that the artificially controlled degradable nanoparticles can serve as an alternative candidate for controllable drug release as well as a platform for highly efficient photothermal-chemo synergistic cancer theranostics.

Indexed as

Magnetic Resonance ImagingAnimalsBehavior, AnimalCell DeathContrast MediaDoxorubicinDrug Delivery SystemsHCT116 CellsHumansHyperthermia, InducedMiceNanoparticlesNeoplasmsPhototherapySerum Albumin, BovineTheranostic NanomedicineContrast MediaDoxorubicinSerum Albumin, Bovinecontrollable drug releasedegradableMRIphotothermalsynergistic therapy

Identifiers

PMID30425480
PMCPMC6205544

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.