Evidence map›Paper›PMID 30425478›Full record

ArticleInternational journal of nanomedicine2018

Evaluation of the internal fixation effect of nano-calcium-deficient hydroxyapatite/poly-amino acid composite screws for intraarticular fractures in rabbits.

Zhenyu Dai, Yue Li, Yonggang Yan, Ruijie Wan, Qiang Ran, Weizhong Lu, Bo Qiao, Hong Li

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Zhenyu DaiDepartment of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, Chongqing, People's Republic of China, zhenyudai1234@163.com.
Yue LiDepartment of Clinical Laboratory, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Yonggang YanCollege of Physical Science and Technology, Sichuan University, Chengdu, People's Republic of China, 564438481@qq.com.
Ruijie WanDepartment of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, Chongqing, People's Republic of China, zhenyudai1234@163.com.
Qiang RanDepartment of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, Chongqing, People's Republic of China, zhenyudai1234@163.com.
Weizhong LuDepartment of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, Chongqing, People's Republic of China, zhenyudai1234@163.com.
Bo QiaoDepartment of Orthopedics, the First Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Hong LiCollege of Physical Science and Technology, Sichuan University, Chengdu, People's Republic of China, 564438481@qq.com.
First People's Hospital of Chongqing · CNSichuan University · CNFirst Affiliated Hospital of Chongqing Medical University · CNInstitute of Clinical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the internal fixation effect of nano-calcium-deficient hydroxyapatite/poly-amino acid (n-CDHA/PAA) composite screws in the intraarticular fracture model. MATERIALS AND

methodsA total of 35 New Zealand White rabbits were used in a bilateral femoral intercondylar fracture model and randomly divided into two groups. n-CDHA/PAA screws were used in the experimental group, and medical metal screws were used in the control group. The fracture condition, range of motion, and the screw push-out strength were assessed, and an arthroscopic examination of knee joint was performed at 4, 8, and 12 weeks after surgery. The biodegradation of the n-CDHA/PAA screws in vivo was tested through weighing, and changes in screw structure were assessed by X-ray diffraction at 12 weeks after surgery.

resultsThe general situation of all animals was good and showed no incision infection and dehiscence after surgery. X-ray scanning showed that significant callus growth was present in both groups at 4 weeks after surgery, and there was no significant difference (

conclusionThe n-CDHA/PAA screw is an effective and safe implant as a potential internal fixation device for an intercondylar fracture of the femur, and its internal fixation effect was similar to that of medical metal screw.

Indexed as

Bone ScrewsFracture Fixation, InternalAmino AcidsAnimalsArthroscopyDurapatiteFemoral FracturesHumansIntra-Articular FracturesKnee JointMaleNanoparticlesRabbitsRange of Motion, ArticularAmino AcidsDurapatitebioactivitybiocompatibilityinternal fixationintraarticular fracturen-CDHA/PAA screw

Identifiers

PMID30425478
PMCPMC6201990
OpenAlexW2896054985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.