Evidence map›Paper›PMID 30425466›Full record

Trial reportClinical interventions in aging2018

Transcutaneous electrical acupoint stimulation for prevention of postoperative delirium in geriatric patients with silent lacunar infarction: a preliminary study.

Fang Gao, Qi Zhang, Yanan Li, Yanlei Tai, Xi Xin, Xiuli Wang, Qiujun Wang

2 registry-linked trialsOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03726073 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Transcutaneous Acupoint Electrical Acupoint Stimulation Combined With Auricular Acupressure on Postoperative Delirium in Elderly Patients Undergoing Major Abdominal Surgery: a Pragmatic Randomized Clinical Trial

TypeinterventionalSponsorAir Force Military Medical University, ChinaRan2019 to 2020Enrolled210ConditionsPostoperative Complications, Postoperative DeliriumArmsTranscutaneous acupoint electrical acupoint stimulation(TEAS) and auricular acupressure, Usual care
NCT04606888 nacompletednot on this mapstarted 2020, after this paper: background citation

Transcutaneous Electrical Acupoint Stimulation for Postoperative Cognitive Dysfunction in Geriatric Patients With Gastrointestinal Tumor

TypeinterventionalSponsorSubei People's Hospital of Jiangsu ProvinceRan2020 to 2020Enrolled64ConditionsPostoperative Cognitive DysfunctionArmsTranscutaneous electrical acupoint stimulation
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Fang GaoDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People's Republic of China, 13933178001@163.com.
Qi ZhangDepartment of Anesthesiology, Children's Hospital of Hebei Province, Shijiazhuang City, Hebei, People's Republic of China.
Yanan LiDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People's Republic of China, 13933178001@163.com.
Yanlei TaiDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People's Republic of China, 13933178001@163.com.
Xi XinDepartment of Anesthesiology, Tianjin Third Central Hospital, Tianjin, People's Republic of China.
Xiuli WangDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People's Republic of China, 13933178001@163.com.
Qiujun WangDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang City, Hebei, People's Republic of China, 13933178001@163.com.
Hebei Medical University · CNThird Hospital of Hebei Medical University · CNHospital of Hebei Province · CNTianjin Third Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to investigate the effect of transcutaneous electrical acupoint stimulation (TEAS) on postoperative delirium (POD) in elderly patients with silent lacunar infarct and preliminarily to determine the relationship among TEAS, blood-brain barrier (BBB), neuroinflammation, and POD. PATIENTS AND

methodsSixty-four-old patients with silent lacunar infarct were randomly divided into two groups: group TEAS and control group (group C). Patients in the group TEAS received TEAS (disperse-dense waves; frequency, 2/100 Hz) on acupoints Hegu and Neiguan of both sides starting from 30 minutes before induction of anesthesia until the end of surgery, and the intensity was the maximum current that could be tolerated. In group C, electrodes were placed on the same acupoints before anesthesia induction, but no current was given. At 0 minute before the treatment of TEAS, 30 minutes after skin incision, and after completion of surgery (T

resultsThis study preliminarily suggests that TEAS can reduce the development of POD in elderly patients with silent lacunar infarction (6.3% vs 25.0%;

conclusionTEAS can alleviate POD in older patients with silent lacunar infarction and may be related to reduce the neuroinflammation by lowering the permeability of BBB.

Indexed as

Acupuncture PointsAgedBlood-Brain BarrierDeliriumFemaleFinlandHumansInflammation MediatorsMaleMiddle AgedNeurologic ExaminationPostoperative ComplicationsPreoperative CareRisk FactorsStroke, LacunarTranscutaneous Electric Nerve StimulationInflammation Mediatorsblood–brain barrierdeliriumgeriatriclacunar infarctionneuroinflammationtranscutaneous electrical acupoint stimulation

Identifiers

PMID30425466
PMCPMC6205526
OpenAlexW2896766350

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.