Evidence map›Paper›PMID 30425464›Full record

ArticleClinical interventions in aging2018

Low skeletal muscle mass as a risk factor for postoperative delirium in elderly patients undergoing colorectal cancer surgery.

Christina Alexa Mosk, Jeroen L A van Vugt, Huub de Jonge, Carlijn Dm Witjes, Stefan Buettner, Jan Nm Ijzermans, Lijckle van der Laan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 11 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 11 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  13. Impact of CGA and Surgical Risk Calculator before elective cancer surgery on postoperative delirium in elderly patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
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  15. Postoperative delirium in patients with cancer: a narrative review of major risk factors.Sao Paulo medical journal = Revista paulista de medicina · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christina Alexa MoskDepartment of Surgery, Amphia Hospital, Breda, the Netherlands.
Jeroen L A van VugtDepartment of Surgery, Erasmus MC University Medical Center, Rotterdam, the Netherlands, j.l.a.vanvugt@erasmusmc.nl.
Huub de JongeDepartment of Surgery, Amphia Hospital, Breda, the Netherlands.
Carlijn Dm WitjesDepartment of Surgery, Erasmus MC University Medical Center, Rotterdam, the Netherlands, j.l.a.vanvugt@erasmusmc.nl.
Stefan BuettnerDepartment of Surgery, Erasmus MC University Medical Center, Rotterdam, the Netherlands, j.l.a.vanvugt@erasmusmc.nl.
Jan Nm IjzermansDepartment of Surgery, Erasmus MC University Medical Center, Rotterdam, the Netherlands, j.l.a.vanvugt@erasmusmc.nl.
Lijckle van der LaanDepartment of Surgery, Amphia Hospital, Breda, the Netherlands.
Erasmus MC · NLAmphia Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Both low skeletal muscle mass (LSMM) and delirium are frequently seen in elderly patients. This study aimed to investigate the association between preoperative LSMM and postoperative delirium (POD) in elderly patients undergoing colorectal cancer (CRC) surgery and to design a model to predict POD. Patients and methods: This is a retrospective observational cohort study. Patients aged 70 years or older undergoing CRC surgery from January 2013 to October 2015 were included in this study. The cross-sectional skeletal muscle area at the level of the third lumbar vertebra using computed tomography was adjusted for patients' height, resulting in the skeletal muscle index. The lowest quartile per sex was defined as LSMM. Short Nutritional Assessment Questionnaire for Residential Care and KATZ-Activities of Daily Living were used to define malnourishment and physical dependency, respectively. POD was diagnosed using the Delirium Observational Screening Scale and geriatricians' notes. Results: Median age of the 251 included patients was 76 years (IQR, 73-80 years), of whom 56% of patients were males, 24% malnourished, and 15% physically impaired. LSMM and POD were diagnosed in 65 and 33 (13%) patients, respectively. POD occurred significantly more in patients with LSMM (25%) compared with patients without LSMM (10%), Conclusion: Age, history of delirium, LSMM, and malnourishment or physical dependency were independently associated with POD. Our nomogram could be used to identify patients at an increased risk for delirium. These patients may benefit from intensive monitoring to prevent POD.

Indexed as

Muscle StrengthAgedAged, 80 and overCohort StudiesColorectal NeoplasmsCorrelation of DataDeliriumDisability EvaluationFemaleHumansMaleNetherlandsPostoperative ComplicationsProtein-Energy MalnutritionRetrospective StudiesRisk Factorscolorectal surgeryelderlynomogrampostoperative deliriumsarcopeniaskeletal muscle mass

Identifiers

PMID30425464
PMCPMC6205536
OpenAlexW2898056207

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.