Evidence map›Paper›PMID 30425236›Full record

ArticleCell death & disease2018

Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis.

Xiufang Xiong, Xia Liu, Haomin Li, Hengqian He, Yi Sun, Yongchao Zhao

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  7. Research Progress of Ribosomal Proteins in Reproductive Development.International journal of molecular sciences · 2024
    Review
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  15. Article
  16. Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins.International journal of molecular sciences · 2021
    Review
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Xiufang XiongInstitute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China. xiufang@zju.edu.cn.
Xia LiuInstitute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China.
Haomin LiInstitute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China.ORCID http://orcid.org/0000-0002-6420-7719
Hengqian HeInstitute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China.
Yi SunInstitute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China. yisun@zju.edu.cn.
Yongchao ZhaoInstitute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China. yongchao@zju.edu.cn.
Zhejiang University · CNChildren's Hospital of Zhejiang University · CNMichigan Cancer Research Consortium · USMinistry of Public Health · MG

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alexey I Nesvizhskii · 1988 to 2026
$178.2M
6 · The paper itself

Abstract

RPS27L (Ribosomal protein S27-like), an evolutionarily conserved ribosomal protein, is a p53 target and a physiological p53 regulator. We previously reported that Rps27l disruption enhanced lymphomagenesis in Trp53

Indexed as

Gene Expression Regulation, NeoplasticAnimalsApoptosisAutophagybeta-Transducin Repeat-Containing ProteinsBreast NeoplasmsCell LineCell Line, TumorChloroquineEpithelial CellsFemaleFibroblastsGenomic InstabilityHumansIntracellular Signaling Peptides and ProteinsMacrolidesbafilomycin A1beta-Transducin Repeat-Containing ProteinsChloroquineDEPTOR protein, humanIntracellular Signaling Peptides and ProteinsMacrolidesMechanistic Target of Rapamycin Complex 1Ribosomal ProteinsRNA, Small InterferingRPS27L protein, humanSKP Cullin F-Box Protein LigasesTumor Suppressor Protein p53

Identifiers

PMID30425236
PMCPMC6234217
OpenAlexW2901155007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.