Evidence map›Paper›PMID 30425072›Full record

ReviewBlood advances2018

When to obtain genomic data in acute myeloid leukemia (AML) and which mutations matter.

Gregory W Roloff, Elizabeth A Griffiths

Open access · goldAbstract readReview
In one paragraph

Review in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Review
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  6. Precision Medicine in Myeloid Malignancies: Hype or Hope?Current hematologic malignancy reports · 2022
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Molecular characterisation ofAfrican journal of laboratory medicine · 2021
    Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gregory W RoloffState University of New York at Buffalo, Buffalo, NY.
Elizabeth A GriffithsNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD; and.
Roswell Park Comprehensive Cancer Center · USUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutational profiling has fundamentally changed our approach to patients with acute myeloid leukemia (AML). Patients with AML are routinely profiled for the presence of mutations in

Indexed as

CCAAT-Enhancer-Binding Proteinsfms-Like Tyrosine Kinase 3HumansLeukemia, Myeloid, AcuteMutationNeoplasm, ResidualNuclear ProteinsNucleophosminRemission InductionRisk FactorsTumor Suppressor Protein p53CCAAT-Enhancer-Binding ProteinsCEBPA protein, humanfms-Like Tyrosine Kinase 3NPM1 protein, humanNuclear ProteinsNucleophosminTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID30425072
PMCPMC6234366
OpenAlexW4234712695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.