Evidence map›Paper›PMID 30425064›Full record

ArticleDiabetes2019

The Familiality of Rapid Renal Decline in Diabetes.

Scott G Frodsham, Zhe Yu, Ann M Lyons, Adhish Agarwal, Melissa H Pezzolesi, Li Dong, Titte R Srinivas, Jian Ying, Tom Greene, Kalani L Raphael and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Observational
  3. Family History in the Context of CKD.Journal of the American Society of Nephrology : JASN · 2025
    Article
  4. Review
  5. [Non-Classical Clinical Types and Pathological Changes of Diabetic Kidney Disease: A Review].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Review
  6. Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (Journal of the American Society of Nephrology : JASN · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Scott G FrodshamDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Zhe YuPopulation Science, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT.
Ann M LyonsHospital Information Technology Services, Enterprise Data Warehouse, University of Utah Hospital and Clinics, Salt Lake City, UT.
Adhish AgarwalDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Melissa H PezzolesiDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Li DongDivision of Nephrology, Intermountain Healthcare, Salt Lake City, UT.
Titte R SrinivasDivision of Nephrology, Intermountain Healthcare, Salt Lake City, UT.
Jian YingDepartment of Population Health Sciences, University of Utah School of Medicine, Salt Lake City, UT.
Tom GreeneDepartment of Population Health Sciences, University of Utah School of Medicine, Salt Lake City, UT.
Kalani L RaphaelDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Ken R SmithPopulation Science, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT.
Marcus G PezzolesiDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT marcus.pezzolesi@hsc.utah.edu.ORCID 0000-0002-4093-3783
University of Utah · USIntermountain Healthcare · USUniversity of Utah Hospital · US

Funding

Coordinating Unit for DiaCompU24DK115255 · NIDDK · AUGUSTA UNIVERSITY · PI MCINDOE, RICHARD A. · 2017 to 2020
$11.6M
NIDDK NIH HHS U24 DK115255
6 · The paper itself

Abstract

Sustained and rapid loss of glomerular filtration rate (GFR) is the predominant clinical feature of diabetic kidney disease and a requisite for the development of end-stage renal disease. Although GFR trajectories have been studied in several cohorts with diabetes and without diabetes, whether rapid renal decline clusters in families with diabetes has not been examined. To determine this, we estimated GFR (eGFR) from serum creatinine measurements obtained from 15,612 patients with diabetes at the University of Utah Health Sciences Center and established their renal function trajectories. Patients with rapid renal decline (eGFR slope < -5 mL/min/1.73 m

Indexed as

AdolescentAdultDiabetic NephropathiesFemaleGlomerular Filtration RateGlycated HemoglobinHumansKidneyMaleMiddle AgedRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsYoung AdultGlycated Hemoglobin

Identifiers

PMID30425064
PMCPMC6341306
OpenAlexW2901207130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.