Evidence map›Paper›PMID 30424824›Full record

ArticleComparative medicine2018

Effects of Intraoperative Vagal Nerve Stimulation on the Gastrointestinal Microbiome in a Mouse Model of Amyotrophic Lateral Sclerosis.

Megan M Haney, Aaron C Ericsson, Teresa E Lever

Open access · greenAbstract read
In one paragraph

Article in Comparative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Megan M HaneyMetagenomics Center, University of Missouri, Columbia, Missouri, USA. haneym@missouri.edu.
Aaron C EricssonMetagenomics Center, University of Missouri, Columbia, Missouri, USA.
Teresa E LeverDepartment of Otolaryngology-Head and Neck Surgery, University of Missouri, Columbia, Missouri, USA.
University of Missouri · US

Funding

Postdoctoral Training in Comparative MedicineT32OD011126 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI Elizabeth C Bryda, Aaron Ericsson · 2012 to 2026
$3.4M
Impact of gut microbiota and segmented filamentous bacteria on colitis-associated colorectal cancerK01OD019924 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI ERICSSON, AARON · 2016 to 2020
$573k
NIH HHS K01 OD019924NIH HHS T32 OD011126
6 · The paper itself

Abstract

The gastrointestinal microbiota (GM) plays a fundamental role in health and disease and contributes to the bidirectional signaling between the gastrointestinal system and brain. The direct line of communication between these organ systems is through the vagus nerve. Therefore, vagal nerve stimulation (VNS), a commonly used technique for multiple disorders, has potential to modulate the enteric microbiota, enabling investigation and possibly treatment of numerous neurologic disorders in which the microbiota has been linked with disease. Here we investigate the effect of VNS in a mouse model of amyotrophic lateral sclerosis (ALS). B6SJL-Tg(SOD1*G93A)

Indexed as

Gastrointestinal MicrobiomeAmyotrophic Lateral SclerosisAnalysis of VarianceAnimalsDisease Models, AnimalMiceMultivariate AnalysisSignal TransductionVagus Nerve Stimulation

Identifiers

PMID30424824
PMCPMC6310200
OpenAlexW2900649992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.