Evidence map›Paper›PMID 30424359›Full record

ArticleMicromachines2018

A Laser-Engraving Technique for Portable Micropneumatic Oscillators.

Vidhya Balaji, Kurt Castro, Albert Folch

Abstract read
In one paragraph

Article in Micromachines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vidhya BalajiDepartment of Electrical Engineering, University of Washington, Seattle, WA 98195, USA. vidb@uw.edu.ORCID 0000-0003-4488-7582
Kurt CastroDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA. castrokb@uw.edu.
Albert FolchDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA. afolch@uw.edu.

Funding

Multiplexed Microfluidic Gradients for Axon GuidanceR01NS064387 · NINDS · UNIVERSITY OF WASHINGTON · PI FOLCH, ALBERT · 2011 to 2015
$1.6M
National Institutes of Health 5R01NS064387NINDS NIH HHS R01 NS064387
6 · The paper itself

Abstract

Microfluidic automation technology is at a stage where the complexity and cost of external hardware control often impose severe limitations on the size and functionality of microfluidic systems. Developments in autonomous microfluidics are intended to eliminate off-chip controls to enable scalable systems. Timing is a fundamental component of the digital logic required to manipulate fluidic flow. The authors present a self-driven pneumatic ring oscillator manufactured by assembling an elastomeric sheet of polydimethylsiloxane (PDMS) between two laser-engraved polymethylmethacrylate (PMMA) layers via surface activation through treatment with 3-aminopropyltriethoxysilane (APTES). The frequency of the fabricated oscillators is in the range of 3⁻7.5 Hz with a maximum of 14 min constant frequency syringe-powered operation. The control of a fluidic channel with the oscillator stages is demonstrated. The fabrication process represents an improvement in manufacturability compared to previous molding or etching approaches, and the resulting devices are inexpensive and portable, making the technology potentially applicable for wider use.

Indexed as

APTES surface activationlaser engravingmanufacturabilitymicrofluidic automationpneumatic oscillator

Identifiers

PMID30424359
PMCPMC6187360

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.