ArticleMicromachines2018
Assembly and Connection of Micropatterned Single Neurons for Neuronal Network Formation.
Article in Micromachines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Biomaterials for neuroengineering: applications and challenges.Regenerative biomaterials · 2025Review
- Network Bursts in 3D Neuron Clusters Cultured on Microcontact-Printed Substrates.Micromachines · 2023Article
- An Overview of In Vitro Biological Neural Networks for Robot Intelligence.Cyborg and bionic systems (Washington, D.C.) · 2023Review
- Advances in construction and modeling of functional neural circuits in vitro.Neurochemical research · 2022Article
- Regulatory Effects of Gradient Microtopographies on Synapse Formation and Neurite Growth in Hippocampal Neurons.Journal of micromechanics and microengineering : structures, devices, and systems · 2022Article
- MatriGridBioengineering (Basel, Switzerland) · 2022Review
- Novel Quick Cell Patterning Using Light-Responsive Gas-Generating Polymer and Fluorescence Microscope.Micromachines · 2022Article
- A neuronal wiring platform through microridges for rationally engineered neural circuits.APL bioengineering · 2020Article
- Bioprinting Neural Systems to Model Central Nervous System Diseases.Advanced functional materials · 2020Review
- A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks.Science advances · 2020Article
- Large-scale acoustic-driven neuronal patterning and directed outgrowth.Scientific reports · 2020Article
- Single-cell patterning technology for biological applications.Biomicrofluidics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Engineering of neuronal network geometry by micropatterning technology is a key future technology for creating artificial brains on a chip. However, engineering of network geometry at the single-cell-level with functional morphology (axon/dendrite) and connectivity (synapses) is still challenging. Here, we describe a method for controlling the axon and dendrite morphology of single primary-cultured neurons and assembling a neural circuit using mobile microplates. The microplates enabled morphological control of neurons by their shapes and bringing their ends into contact caused the formation of physical connections. Functional synapse formation at the connection was indicated by immunostaining of synapse-related proteins and intracellular Ca
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.