Evidence map›Paper›PMID 30424090›Full record

ArticleMicromachines2018

An FEP Microfluidic Reactor for Photochemical Reactions.

Tomasz Szymborski, Paweł Jankowski, Dominika Ogończyk, Piotr Garstecki

Abstract read
In one paragraph

Article in Micromachines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tomasz SzymborskiInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland. tszymborski@ichf.edu.pl.
Paweł JankowskiInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland. pjankowski@ichf.edu.pl.
Dominika OgończykInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland. dogonczyk@ichf.edu.pl.
Piotr GarsteckiInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland. garst@ichf.edu.pl.ORCID 0000-0001-9101-7163

Funding

Foundation for Polish Science Idee dla PolskiNanoFun POIG.02.02.00-00-025/09
6 · The paper itself

Abstract

Organic syntheses based on photochemical reactions play an important role in the medical, pharmaceutical, and polymeric chemistry. For years, photochemistry was performed using high-pressure mercury lamps and immersion-wells. However, due to excellent yield, control of temperature, selectivity, low consumption of reagents and safety, the microreactors made of fluorinated ethylene propylene (FEP) tubings have recently been used more frequently. Fluoropolymers are the material of choice for many types of syntheses due to their chemical compatibility and low surface energy. The use of tubing restricts the freedom in designing 2D and 3D geometries of the sections of the microreactors, mixing sections, etc., that are easily achievable in the format of a planar chip. A chip microreactor made of FEP is impracticable to develop due to its high chemical inertness and high melting temperature, both of which make it difficult (or impossible) to bond two plates of polymer. Here, we demonstrate a 'click' system, where the two plates of FEP are joined together mechanically using a tenon and a mortise. The concept was presented by us previously for a preparation polytetrafluoroethylene (PTFE) microreactor (Szymborski et al.

Indexed as

fluorinated ethylene propylene (FEP)microreactororganic synthesisphotochemistry

Identifiers

PMID30424090
PMCPMC6187735

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.