Evidence map›Paper›PMID 30424052›Full record

ArticleMicromachines2018

Determination of the Three-Dimensional Rate of Cancer Cell Rotation in an Optically-Induced Electrokinetics Chip Using an Optical Flow Algorithm.

Yuliang Zhao, Dayu Jia, Xiaopeng Sha, Guanglie Zhang, Wen Jung Li

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yuliang ZhaoSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066004, China. zhaoyuliang@neuq.edu.cn.
Dayu JiaSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066004, China. jiadayu.neu@gmail.com.
Xiaopeng ShaSchool of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066004, China. Shaxiaopeng@neuq.edu.cn.
Guanglie ZhangShenzhen Academy of Robotics, Shenzhen 518000, China. guanglie.zhang@gmail.com.
Wen Jung LiDepartment of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong 999077, China. wenjli@cityu.edu.hk.
Northeastern University · CNCity University of Hong Kong · HKShenzhen Academy of Robotics · CN

Funding

National Natural Science Foundation of China 61503322
6 · The paper itself

Abstract

Our group has reported that Melan-A cells and lymphocytes undergo self-rotation in a homogeneous AC electric field, and found that the rotation velocity of these cells is a key indicator to characterize their physical properties. However, the determination of the rotation properties of a cell by human eyes is both gruesome and time consuming, and not always accurate. In this paper, a method is presented to more accurately determine the 3D cell rotation velocity and axis from a 2D image sequence captured by a single camera. Using the optical flow method, we obtained the 2D motion field data from the image sequence and back-project it onto a 3D sphere model, and then the rotation axis and velocity of the cell were calculated. After testing the algorithm on animated image sequences, experiments were also performed on image sequences of real rotating cells. All of these results indicate that this method is accurate, practical, and useful. Furthermore, the method presented there can also be used to determine the 3D rotation velocity of other types of spherical objects that are commonly used in microfluidic applications, such as beads and microparticles.

Indexed as

cell self-rotationoptical flow algorithmoptically induced electrokineticssingle cell rotation

Identifiers

PMID30424052
PMCPMC6187528
OpenAlexW2793001320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.