ArticlePharmaceutics2018
Experimental and Modeling Study of Drug Release from HPMC-Based Erodible Oral Thin Films.
Article in Pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Article
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- Development of a Multilayer Film Including the Soluble Eggshell Membrane Fraction for the Treatment of Oral Mucosa Lesions.Pharmaceutics · 2024Article
- Experimental and Modelling Study of Controlled Release from Dextran-Based Cryogels.Pharmaceutics · 2024Article
- Hypromellose-, Gelatin- and Gellan Gum-Based Gel Films with Chlorhexidine for Potential Application in Oral Inflammatory Diseases.Gels (Basel, Switzerland) · 2024Article
- Enhancing Pharmacokinetics and Pharmacodynamics of Rosuvastatin Calcium through the Development and Optimization of Fast-Dissolving Films.Pharmaceutics · 2023Article
- Article
- A pH-Controlled Solid Inhibitor Based onMolecules (Basel, Switzerland) · 2023Article
- Fast-dissolving oral films containing dextromethorphan/phenylephrine for sinusitis treatment: formulation, characterization and optimization.Progress in biomaterials · 2022Article
- Development, Evaluation, and Molecular Docking of Oral Dissolving Film of Atenolol.Pharmaceutics · 2021Article
- 3D Printing of Drug Nanocrystals for Film Formulations.Molecules (Basel, Switzerland) · 2021Article
- Swelling and Drug Release in Polymers through the Theory of Poisson-Kac Stochastic Processes.Gels (Basel, Switzerland) · 2021Article
- Enhanced Loading Efficiency and Mucoadhesion Properties of Gellan Gum Thin Films by Complexation with Hydroxypropyl-Pharmaceutics · 2020Article
- In vitro and in vivo evaluation of gentamicin sulphate-loaded PLGA nanoparticle-based film for the treatment of surgical site infection.Drug delivery and translational research · 2020Article
- The Process⁻Property⁻Performance Relationship of Medicated Nanoparticles Prepared by Modified Coaxial Electrospraying.Pharmaceutics · 2019Article
- Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release.Pharmaceutics · 2019Article
- Drug Release Profiles and Disintegration Properties of Pectin Films.Materials (Basel, Switzerland) · 2019Article
- Oral thin film containing rice husk liquid smoke effects on the expression of key cytokines and growth factors in a periodontitis model.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
In this work hydroxypropyl methylcellulose (HPMC) fast-dissolving thin films for oral administration are investigated. Furosemide (Class IV of the Biopharmaceutical Classification System) has been used as a model drug for in vitro release tests using three different set-ups: the Franz cell, the millifluidic flow-through device, and the paddle type dissolution apparatus (USP II). In order to enable drug incorporation within HPMC films, a multifunctional excipient, hydroxypropyl- β -cyclodextrin (HP- β -CD) has been included in the formulation, and the influence of HP- β -CD on film swelling, erosion, and release properties has been investigated. Mathematical models capable of describing the swelling and release processes from HPMC erodible thin films in different apparatuses have been developed. In particular, we propose a new model for the description of drug transport and release in a Franz cell that accounts for the effect of the unavoidable imperfect mixing of the receptor chamber.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.