Evidence map›Paper›PMID 30423933›Full record

ArticleMolecules (Basel, Switzerland)2018

A Genomic Survey of Angiotensin-Converting Enzymes Provides Novel Insights into Their Molecular Evolution in Vertebrates.

Yunyun Lv, Yanping Li, Yunhai Yi, Lijun Zhang, Qiong Shi, Jian Yang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. SARS CoV-2 Spike ProteinFrontiers in genetics · 2021
    Article
  6. Molecular evolution and phylogenetic analysis of SARS-CoV-2 and hosts ACE2 protein suggest Malayan pangolin as intermediary host.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  7. Article
  8. Article
  9. Covid-19, ACE2 and the kidney.Acta physiologica (Oxford, England) · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yunyun LvSchool of Applied Chemistry and Biotechnology, Shenzhen Polytechnic, Shenzhen 518055, China. lvyunyun@genomics.cn.
Yanping LiShenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen 518083, China. liyanping@genomics.cn.
Yunhai YiBGI Education Center, University of Chinese Academy of Sciences, Shenzhen 518083, China. yiyunhai@genomics.cn.ORCID 0000-0002-3516-6700
Lijun ZhangSchool of Applied Chemistry and Biotechnology, Shenzhen Polytechnic, Shenzhen 518055, China. c7zlj@szpt.edu.cn.
Qiong ShiBGI Education Center, University of Chinese Academy of Sciences, Shenzhen 518083, China. shiqiong@genomics.cn.ORCID 0000-0002-6358-976X
Jian YangSchool of Applied Chemistry and Biotechnology, Shenzhen Polytechnic, Shenzhen 518055, China. jiany@szpt.edu.cn.

Funding

Science and Technology Project of Shenzhen JCYJ20170413155047512Shenzhen High Technology Research and Development Program JSGG20150916140818695Yunnan Innovation and Enhancement Program of Provincial Science and Technology Department 2016AB024
6 · The paper itself

Abstract

Angiotensin-converting enzymes, ACE and ACE2, are two main elements in the renin⁻angiotensin system, with a crucial role in the regulation of blood pressure in vertebrates. Previous studies paid much attention to their physiological functions in model organisms, whereas the studies on other animals and related evolution have been sparse. Our present study performed a comprehensive genomic investigation on

Indexed as

Evolution, MolecularGenomicsAngiotensin IIAnimalsExonsGenetic VariationPeptidyl-Dipeptidase APhylogenyRenin-Angiotensin SystemSignal TransductionVertebratesAngiotensin IIPeptidyl-Dipeptidase Aangiotensin-converting enzymeevolutiongenomic comparisonphylogeny

Identifiers

PMID30423933
PMCPMC6278350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.