Evidence map›Paper›PMID 30423859›Full record

ArticleNutrients2018

Association of Serum 25-Hydroxyvitamin D Concentration with Pulmonary Function in Young Adults.

Vanda Craveiro, Maria Cabral, Joana Araújo, Helena Falcão, João Tiago Guimarães, Elisabete Ramos

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Vitamin D and SARS-CoV-2 virus/COVID-19 disease.BMJ nutrition, prevention & health · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vanda CraveiroEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, nº 135, 4050-600 Porto, Portugal. vandacraveiro@gmail.com.
Maria CabralUnidade de Epidemiologia-Departamento de Ciências da Saúde Pública e Forenses e Educação Médica da Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal. maria.cabral@ispup.up.pt.
Joana AraújoEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, nº 135, 4050-600 Porto, Portugal. joana.araujo@ispup.up.pt.ORCID 0000-0001-9649-3177
Helena FalcãoServiço de Imunoalergologia do Centro Hospitalar do Porto, E.P.E., 4099-001 Porto, Portugal. falcao.helena@gmail.com.
João Tiago GuimarãesEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, nº 135, 4050-600 Porto, Portugal. jtguimar@med.up.pt.ORCID 0000-0003-4836-6311
Elisabete RamosEPIUnit-Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, nº 135, 4050-600 Porto, Portugal. eliramos@med.up.pt.
Universidade do Porto · PTCentro Hospitalar do Porto · PT

Funding

FCT and the POPH/FSE Program PD/BD/105824/2014FEDER through the Operational Programme Competitiveness and Internationalization POCI-01-0145-FEDER-016829Fundação para a Ciência e a Tecnologia FCT PTDC/DTP-EPI/6506/2014
6 · The paper itself

Abstract

The role of vitamin D on pulmonary function is unclear and is mostly studied in patients, smokers and elderly people. The aim of this paper was to evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] concentration and pulmonary function in young adults. Cross-sectional analysis of 499 individuals that were evaluated at 21 years of age as part of the population-based cohort Epidemiological Health Investigation of Teenagers in Porto (EPITeen). Serum 25(OH)D was categorized according to the Institute of Medicine. Pulmonary function was evaluated using spirometry. Linear regression models were used to estimate the regression coefficients (β) and its 95% confidence intervals (95% CI), and were adjusted for confounders. Education, smoking, body mass index, and season of evaluation were determinants of serum 25(OH)D concentration. Prevalence of serum 25(OH)D concentration <50 nmol/L was 48.9%. A decrease in all pulmonary function parameters, with the decrease of serum 25(OH)D, was observed. The higher effect was found for peak expiratory flow (PEF). Having as reference participants with serum 25(OH)D concentration ≥50 nmol/L, PEF was significantly lower for those with a concentration of 30 to <50 nmol/L (β= -0.576; 95% CI: -0.943, -0.210), and for those with a concentration of <30 nmol/L (β= -0.650; 95% CI: -1.155, -0.146). Although only PEF attained statistical significance, the consistent results with the other parameters support the role of serum 25(OH)D to promote better pulmonary function in young adults.

Indexed as

AdultCohort StudiesCross-Sectional StudiesExhalationFemaleHumansLinear ModelsLungMalePortugalPrevalenceSpirometryVitamin DVitamin D DeficiencyYoung Adult25-hydroxyvitamin DVitamin D25-hydroxyvitamin Dpulmonary functionspirometryvitamin Dyoung adults

Identifiers

PMID30423859
PMCPMC6266201
OpenAlexW2739999669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.