Evidence map›Paper›PMID 30423799›Full record

ArticleCells2018

Matrix Metalloproteinase-1 and Acid Phosphatase in the Degradation of the Lamina Propria of Eruptive Pathway of Rat Molars.

José Paulo de Pizzol Júnior, Estela Sasso-Cerri, Paulo Sérgio Cerri

Open access · goldAbstract read
In one paragraph

Article in Cells, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

José Paulo de Pizzol JúniorDepartment of Morphology and Genetics, Federal University of São Paulo (UNIFESP), 04021-001 São Paulo, SP, Brazil. jpaulopizzol@gmail.com.
Estela Sasso-CerriLaboratory of Histology and Embryology-Araraquara, School of Dentistry, São Paulo State University (UNESP), 1680 Centro, CEP 14801⁻903 Araraquara, SP, Brazil. estela.sasso@unesp.br.
Paulo Sérgio CerriLaboratory of Histology and Embryology-Araraquara, School of Dentistry, São Paulo State University (UNESP), 1680 Centro, CEP 14801⁻903 Araraquara, SP, Brazil. paulo.cerri@unesp.br.ORCID 0000-0001-5756-5828
Centro Universitário de Araraquara · BRUniversidade Federal de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 309533/2015-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2010/10391-9; 2011/23064-9; 2016/09264-9
6 · The paper itself

Abstract

The comprehension of dental pathogenesis and disorders derived from eruption failure requires a deep understanding of the molecular mechanisms underlying normal tooth eruption. As intense remodelling is needed during tooth eruption, we hypothesize that matrix metalloproteinase-1 (MMP-1) and acid phosphatase (ACP) play a role in the eruptive pathway degradation. We evaluated MMP-1-immunoexpression and the collagen content in the lamina propria at different eruptive phases. Immunohistochemistry and ultrastructural cytochemistry for detection of ACP were also performed. In the maxillary sections containing first molars of 9-, 11-, 13-, and 16-day-old rats, the birefringent collagen of eruptive pathway was quantified. MMP-1 and ACP-2 immunohistochemical reactions were performed and the number of MMP-1-immunolabelled cells was computed. Data were analyzed by one-way ANOVA and Tukey post-test (

Indexed as

acid phosphatasebirefringent collageneruptive pathwaylamina propriamatrix metalloproteinase-1ultrastructure

Identifiers

PMID30423799
PMCPMC6262441
OpenAlexW2899535517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.