Evidence map›Paper›PMID 30423481›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2019

Effect of Conditioning Regimen Dose Reduction in Obese Patients Undergoing Autologous Hematopoietic Cell Transplantation.

Claudio G Brunstein, Marcelo C Pasquini, Soyoung Kim, Mingwei Fei, Kehinde Adekola, Ibrahim Ahmed, Mahmoud Aljurf, Vaibhav Agrawal, Jeffrey J Auletta, Minoo Battiwalla and 32 more

Open access · greenAbstract read
In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 6 countries.

Claudio G BrunsteinBlood and Marrow Transplant Program, University of Minnesota, Minneapolis, MN, USA.
Marcelo C PasquiniCIBMTR(®) (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address: mpasquini@mcw.edu.
Soyoung KimCIBMTR(®) (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA; Division of Biostatistics, Institute for Health and Society, Medical College of Wisconsin, Milwaukee, WI, USA.
Mingwei FeiCIBMTR(®) (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Kehinde AdekolaDivision of Hematology/Oncology, Department of Medicine and Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Ibrahim AhmedDepartment of Hematology Oncology and Bone Marrow Transplantation, The Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
Mahmoud AljurfDepartment of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh, Saudi Arabia.
Vaibhav AgrawalDivision of Hematology/Oncology, Indiana University Simon Cancer Center, Indianapolis, IN, USA.
Jeffrey J AulettaBlood and Marrow Transplant Program and Host Defense Program, Divisions of Hematology/Oncology/Bone Marrow Transplant and Infectious Diseases, Nationwide Children's Hospital, Columbus, OH, USA.
Minoo BattiwallaHematology Branch, Sarah Cannon BMT Program, Nashville, TN, USA.
Nelli BejanyanDepartment of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Joseph BubaloAdult Blood and Marrow Stem Cell Transplant Program, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.
Jan CernyDivision of Hematology/Oncology, Department of Medicine, University of Massachusetts Medical Center, Worcester, MA, USA.
Lynette CheeThe Royal Melbourne Hospital, Melbourne, Australia.
Stefan O CiureaUniversity of Texas and MD Anderson Cancer Center, Houston, TX, USA.
Cesar FreytesTexas Transplant Institute, San Antonio, TX, USA.
Shahinaz M GadallaDivision of Cancer Epidemiology & Genetics, NIH-NCI Clinical Genetics Branch, Rockville, MD, USA.
Robert Peter GaleHematology Research Centre, Division of Experimental Medicine, Department of Medicine, Imperial College London, London, United Kingdom.
Siddhartha GangulyDivision of Hematological Malignancy and Cellular Therapeutics, University of Kansas Health System, Kansas City, KS, USA.
Shahrukh K HashmiDepartment of Internal Medicine, Mayo Clinic, MN, USA; Department of Oncology, King Faisal Specialist Hospital Center & Research, Riyadh, Saudi Arabia.
Peiman HemattiDivision of Hematology/Oncology/Bone Marrow Transplantation, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, WI, USA.
Gerhard HildebrandtMarkey Cancer Center, University of Kentucky, Lexington, KY, USA.
Leona A HolmbergFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Oscar B LahoudBone Marrow Transplant Service, Division of Hematology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Heather LandauBone Marrow Transplant Service, Division of Hematology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Hillard M LazarusCase Western Reserve University, Cleveland, OH, USA.
Marcos de LimaDepartment of Medicine, Seidman Cancer Center, University Hospitals Case Medical Center, Cleveland, OH, USA.
Vikram MathewsDepartment of Hematology, Christian Medical College & Hospital, Vellore, India.
Richard MaziarzAdult Blood and Marrow Stem Cell Transplant Program, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.
Taiga NishihoriDepartment of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Maxim NorkinDivision of Hematology/Oncology, University Florida College of Medicine, Gainesville, FL, USA.
Richard OlssonDivision of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Centre for Clinical Research Sormland, Uppsala University, Uppsala, Sweden.
Ran ReshefBlood and Marrow Transplantation Program and Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY, USA.
Seth RotzCincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Bipin SavaniDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Harry C SchoutenDepartment of Hematology, Academische Ziekenhuis, Maastricht, Netherlands.
Sachiko SeoVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Baldeep M WirkStony Brook University Medical Center, Stony Brook, NY, USA.
Jean YaredBlood & Marrow Transplantation Program, Division of Hematology/Oncology, Department of Medicine, Greenebaum Cancer Center, University of Maryland, Baltimore, MD, USA.
Shin MineishiPenn State Health Hershey Medical Center, Hershey, PA, USA.
John RogosheskeBlood and Marrow Transplant Program, University of Minnesota, Minneapolis, MN, USA.
Miguel-Angel PeralesAdult Bone Marrow Transplant Services, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Medical College of Wisconsin · USMemorial Sloan Kettering Cancer Center · USFred Hutch Cancer Center · USKing Faisal Specialist Hospital & Research Centre · SAMoffitt Cancer Center · USOregon Health & Science University · USUniversity of Minnesota · USCancer Genetics (United States) · USCase Western Reserve University · USChildren's Mercy Hospital · USChristian Medical College, Vellore · INCHRISTUS Transplant Institute · USCincinnati Children's Hospital Medical Center · USColumbia University Irving Medical Center · USFlorida College · USImperial College London · GBIndiana University Health · USNationwide Children's Hospital · USNorthwestern University · USPenn State Milton S. Hershey Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
Easy-to-read Informed Consent for HCT Clinical TrialsU10HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2011 to 2016
$43.8M
BMT CTN Core - University of MinnesotaUG1HL069290 · NHLBI · UNIVERSITY OF MINNESOTA · PI Mark Juckett, Margaret L MacMillan · 2017 to 2026
$1.9M
NCI NIH HHS P30 CA008748NCI NIH HHS U24 CA076518NHLBI NIH HHS U10 HL069294NHLBI NIH HHS UG1 HL069290
6 · The paper itself

Abstract

Data are limited on whether to adjust high-dose chemotherapy before autologous hematopoietic cell transplant (autoHCT) in obese patients. This study explores the effects of dose adjustment on the outcomes of obese patients, defined as body mass index (BMI) ≥ 30 kg/m

Indexed as

Drug Dosage CalculationsObesityAdultAgedAntineoplastic AgentsFemaleHematopoietic Stem Cell TransplantationHumansLymphomaMaleMiddle AgedMortalityMultiple MyelomaRecurrenceTransplantation, AutologousTransplantation ConditioningAntineoplastic AgentsAutologous hematopoietic cell transplantationConditioning regimenObesity

Identifiers

PMID30423481
PMCPMC6445718
OpenAlexW2900021855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.