Evidence map›Paper›PMID 30423480›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2019

Effect of Aging and Predonation Comorbidities on the Related Peripheral Blood Stem Cell Donor Experience: Report from the Related Donor Safety Study.

Michael A Pulsipher, Brent R Logan, Pintip Chitphakdithai, Deidre M Kiefer, Marcie L Riches, J Douglas Rizzo, Paolo Anderlini, Susan F Leitman, James W Varni, Hati Kobusingye and 52 more

Open access · hybridAbstract read
In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Turkish Hematologists’ Preferences for Related Donor Selection: Results of a Multicenter SurveyTurkish journal of haematology : official journal of Turkish Society of Haematology · 2024
    Article
  5. The Relationship between the Lifestyle of the Allogeneic Stem Cell Donors and the Number of Donated CD34International journal of hematology-oncology and stem cell research · 2024
    Article
  6. Article
  7. Article
  8. Supportive Care of Hematopoietic Stem Cell Donors.Clinical hematology international · 2024
    Article
  9. Review
  10. Observational
  11. Health-Related Quality-of-Life Comparison of Adult Related and Unrelated HSC Donors: An RDSafe Study.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
  12. Higher Risks of Toxicity and Incomplete Recovery in 13- to 17-Year-Old Females after Marrow Donation: RDSafe Peds Results.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

62 authors at 20 institutions in 1 country.

Michael A PulsipherChildren's Hospital Los Angeles, Division of Hematology, Oncology, and Blood and Marrow Transplantation, Los Angeles, California. Electronic address: mpulsipher@chla.usc.edu.
Brent R LoganCenter for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin.
Pintip ChitphakdithaiCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota.
Deidre M KieferCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota.
Marcie L RichesUniversity of North Carolina Hospitals, Division of Hematology and Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
J Douglas RizzoCenter for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin.
Paolo AnderliniM.D. Anderson Cancer Center, Department of Stem Cell Transplantation and Cellular Therapy, Houston, Texas.
Susan F LeitmanDepartment of Transfusion Medicine, National Institutes of Health Clinical Center, Bethesda, Maryland.
James W VarniTexas A & M University, Department of Pediatrics, College Station, Texas.
Hati KobusingyeCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota.
RaeAnne M BesserCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota.
John P MillerNational Marrow Donor Program/Be the Match, Minneapolis, Minnesota.
Rebecca J DrexlerCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota.
Aly Abdel-MageedHelen DeVos Children's Hospital, Grand Rapids, Michigan.
Ibrahim A AhmedChildren's Mercy Hospitals and Clinics, Kansas City, Missouri.
Luke P AkardIndiana Blood and Marrow Transplantation, Indianapolis, Indiana.
Andrew S ArtzUniversity of Chicago Hospitals, Chicago, Illinois.
Edward D BallUniversity of California, San Diego Medical Center, La Jolla, California.
Ruthee-Lu BayerNorth Shore University Hospital, Manhasset, New York.
Carolyn BigelowUniversity of Mississippi Medical Center, Jackson, Mississippi.
Brian J BolwellCleveland Clinic Foundation, Cleveland, Ohio.
E Randolph BrounJewish Hospital, Cincinnati, Ohio.
Nancy J BuninChildren's Hospital of Philadelphia, Division of Oncology, Philadelphia, Pennsylvania.
David C DelgadoIndiana University Hospital/Riley Hospital for Children, Indianapolis, Indiana.
Katharine DuckworthWake Forest University Baptist Medical Center, Winston-Salem, North Carolina.
Christopher C DvorakUniversity of California San Francisco Benioff Children's Hospital, Division of Pediatric Blood and Marrow Transplantation San Francisco, California.
Theresa E HahnRoswell Park Cancer Institute, Buffalo, New York.
Ann E HaightAflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, Georgia.
Parameswaran N HariDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Brandon M Hayes-LattinDoernbecher Children's Hospital, Oregon Health & Science University, Portland, Oregon.
David A JacobsohnChildren's National Medical Center, Washington, DC.
Ann A JakubowskiMemorial Sloan Kettering Cancer Center-Adult, New York, New York.
Kimberly A KasowUniversity of North Carolina Healthcare, Chapel Hill, North Carolina.
Hillard M LazarusSeidman Cancer Center-University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Jane L LiesveldStrong Memorial Hospital, University of Rochester Medical Center, Rochester, New York.
Michael LinenbergerFred Hutchinson Cancer Research Center, Seattle, Washington.
Mark R LitzowMayo Clinic Rochester, Rochester, Minnesota.
Walter LongoUniversity of Wisconsin Hospital and Clinics, Madison, Wisconsin.
Margarida Magalhaes-SilvermanUniversity of Iowa Hospitals & Clinics, Iowa City, Iowa.
John M McCartyVirginia Commonwealth University Massey Cancer Center Bone Marrow Transplant Program, Richmond, Virginia.
Joseph P McGuirkUniversity of Kansas, Westwood, Kansas.
Shahram MoriFlorida Hospital Cancer Institute, Florida Center for Cellular Therapy, Orlando, Florida.
Vinod K PrasadDuke University Medical Center, Durham, North Carolina.
Scott D RowleyHackensack University Medical Center, Washington, DC.
Witold B RybkaPenn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.
Indira SahdevCohen Children's Medical Center of New York, New Hyde Park, New York.
Jeffrey R SchriberCancer Transplant Institute Honor Health, Scottsdale, Arizona.
George B SelbyHCA Health Services of Oklahoma, Inc., University of Oklahoma, Oklahoma City, OK.
Paul J ShaughnessyTexas Transplant Institute, San Antonio, Texas.
Shalini ShenoySt. Louis Children's Hospital, St. Louis, Missouri.
Thomas SpitzerMassachusetts General Hospital, Boston, Massachusetts.
William T TseAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Joseph P UbertiKarmanos Cancer Institute, Detroit, Michigan.
Madhuri VusirikalaUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Edmund K WallerEmory University Hospital, Atlanta, Georgia.
Daniel J WeisdorfUniversity of Minnesota Medical Center, Fairview, Minneapolis, Minnesota.
Gregory A YanikThe University of Michigan, Ann Arbor, Michigan.
Willis H NavarroCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota.
Mary M HorowitzCenter for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin.
Galen E SwitzerUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Bronwen E ShawCenter for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin.
Dennis L ConferCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota; National Marrow Donor Program/Be the Match, Minneapolis, Minnesota.
Medical College of Wisconsin · USNational Marrow Donor Program · USAtrium Health Wake Forest Baptist · USChildren's Hospital of Los Angeles · USChildren's Hospital of Philadelphia · USChildren's Mercy Hospital · USChildren's National · USCHRISTUS Transplant Institute · USCleveland Clinic · USCohen Children's Medical Center · USDuke Medical Center · USEmory University · USEmory University Hospital · USFlorida Hospital Cancer Institute · USFred Hutch Cancer Center · USHackensack University Medical Center · USHelen DeVos Children's Hospital · USHonorHealth · USIndiana Cancer Consortium · USIndiana University Hospital · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.U24HL138660 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Steven M. DeVine, Mehdi Hussain Hamadani · 2017 to 2026
$71.4M
RDSafe: A Multi-Institutional Study of HSC Donor Safety and Quality LifeR01HL085707 · NHLBI · UNIVERSITY OF UTAH · PI PULSIPHER, MICHAEL A, SWITZER, GALEN E. · 2009 to 2013
$3.1M
Unrelated Donor BMT vs. Immune Suppression for Newly Diagnosed Severe Aplastic Anemia in Children and Young Adults: BMT CTN Core Center Renewal for the Pediatric Blood and Marrow Transplant ConsortiumUG1HL069254 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI KEAN, LESLIE S · 2017 to 2023
$1.3M
NCI NIH HHS P30 CA008748NCI NIH HHS U24 CA076518NHLBI NIH HHS R01 HL085707NHLBI NIH HHS U24 HL138660NHLBI NIH HHS UG1 HL069254
6 · The paper itself

Abstract

The development of reduced-intensity approaches for allogeneic hematopoietic cell transplantation has resulted in growing numbers of older related donors (RDs) of peripheral blood stem cells (PBSCs). The effects of age on donation efficacy, toxicity, and long-term recovery in RDs are poorly understood. To address this we analyzed hematologic variables, pain, donation-related symptoms, and recovery in 1211 PBSC RDs aged 18 to 79 enrolled in the Related Donor Safety Study. RDs aged > 60 had a lower median CD34

Indexed as

AdolescentAdultAgedBlood DonorsComorbidityFemaleHumansMaleMiddle AgedPeripheral Blood Stem CellsPeripheral Blood Stem Cell TransplantationYoung AdultBM collection toxicitiesDonor safetyPBSC collection toxicitiesStem cell transplantation

Identifiers

PMID30423480
PMCPMC6453753
OpenAlexW2900420483

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.